Journal article
Performance of the Mood Disorder Questionnaire (MDQ) according to bipolar subtype and symptom severity.
- Gervasoni N Service of Adult Psychiatry, Department of Psychiatry, University Hospitals of Geneva, Switzerland.
- Weber Rouget B
- Miguez M
- Dubuis V
- Bizzini V
- Gex-Fabry M
- Bondolfi G
- Aubry JM
- 2009-02-10
Published in:
- European psychiatry : the journal of the Association of European Psychiatrists. - 2009
Adult
Bipolar Disorder
Depressive Disorder
Diagnosis, Differential
Female
Humans
Male
Middle Aged
Personality Inventory
Psychometrics
Reproducibility of Results
Young Adult
English
OBJECTIVE
To evaluate the performance of the French version of the Mood Disorder Questionnaire (MDQ) in patients attending a general psychiatric outpatient service as well as whether MDQ scores are independent of patient mood state at time of completion.
METHOD
183 patients completed the MDQ and were assessed with the MADRS and YMRS scales, before being interviewed with the SCID (time 1). MDQ, MADRS and YMRS assessment was repeated four to six weeks later (time 2).
RESULTS
According to the SCID, 44 patients were suffering from bipolar spectrum disorder and 102 from unipolar disorder (37 patients dropped out). The MDQ provided high specificity (83.3%). Sensitivity was 63.6%, with better identification of bipolar I (85.0%) than bipolar II patients (45.8%). In the whole sample, test-retest reliability was satisfactory (kappa=0.64). Modest correlations were observed between the number of endorsed MDQ items and YMRS scores at time 1 (Spearman r=0.19; p=0.021) and time 2 (r=0.26; p=0.002).
CONCLUSIONS
Despite some fluctuations over time and a discrete influence of symptom severity, the screening algorithm can be used reliably, whether in the acute or remission phase of a depressive episode.
To evaluate the performance of the French version of the Mood Disorder Questionnaire (MDQ) in patients attending a general psychiatric outpatient service as well as whether MDQ scores are independent of patient mood state at time of completion.
METHOD
183 patients completed the MDQ and were assessed with the MADRS and YMRS scales, before being interviewed with the SCID (time 1). MDQ, MADRS and YMRS assessment was repeated four to six weeks later (time 2).
RESULTS
According to the SCID, 44 patients were suffering from bipolar spectrum disorder and 102 from unipolar disorder (37 patients dropped out). The MDQ provided high specificity (83.3%). Sensitivity was 63.6%, with better identification of bipolar I (85.0%) than bipolar II patients (45.8%). In the whole sample, test-retest reliability was satisfactory (kappa=0.64). Modest correlations were observed between the number of endorsed MDQ items and YMRS scores at time 1 (Spearman r=0.19; p=0.021) and time 2 (r=0.26; p=0.002).
CONCLUSIONS
Despite some fluctuations over time and a discrete influence of symptom severity, the screening algorithm can be used reliably, whether in the acute or remission phase of a depressive episode.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1016/j.eurpsy.2008.12.008
- PMID 19200693
- Persistent URL
- https://sonar.ch/global/documents/169723
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