Journal article
Prevalence and correlates of psychiatric comorbidities in children and adolescents with full and subthreshold avoidant/restrictive food intake disorder.
- Kambanis PE Department of Psychology, University of Wyoming, Laramie, Wyoming.
- Kuhnle MC Eating Disorders Clinical and Research Program, Massachusetts General Hospital, Boston, Massachusetts.
- Wons OB Eating Disorders Clinical and Research Program, Massachusetts General Hospital, Boston, Massachusetts.
- Jo JH Eating Disorders Clinical and Research Program, Massachusetts General Hospital, Boston, Massachusetts.
- Keshishian AC Eating Disorders Clinical and Research Program, Massachusetts General Hospital, Boston, Massachusetts.
- Hauser K Neuroendocrine Unit, Massachusetts General Hospital, Boston, Massachusetts.
- Becker KR Eating Disorders Clinical and Research Program, Massachusetts General Hospital, Boston, Massachusetts.
- Franko DL Eating Disorders Clinical and Research Program, Massachusetts General Hospital, Boston, Massachusetts.
- Misra M Neuroendocrine Unit, Massachusetts General Hospital, Boston, Massachusetts.
- Micali N Département universitaire de psychiatrie, Université de Genève, Genève, Switzerland.
- Lawson EA Neuroendocrine Unit, Massachusetts General Hospital, Boston, Massachusetts.
- Eddy KT Eating Disorders Clinical and Research Program, Massachusetts General Hospital, Boston, Massachusetts.
- Thomas JJ Eating Disorders Clinical and Research Program, Massachusetts General Hospital, Boston, Massachusetts.
- 2019-11-09
Published in:
- The International journal of eating disorders. - 2020
ARFID
anxiety disorders
avoidant/restrictive food intake disorder
comorbidity
diagnosis
structured interview
suicidality
Adolescent
Adult
Avoidant Restrictive Food Intake Disorder
Child
Comorbidity
Feeding and Eating Disorders
Female
Humans
Male
Prevalence
Psychopathology
Young Adult
English
OBJECTIVE
We aimed to characterize the current and lifetime prevalence of comorbid psychiatric diagnoses and suicidality in treatment- and nontreatment-seeking individuals with full and subthreshold avoidant/restrictive food intake disorder (ARFID). We also sought to examine unique associations between the three DSM-5 ARFID profiles (i.e., sensory sensitivity, fear of aversive consequences, and lack of interest in food or eating) and specific categories of psychiatric diagnoses and suicidality.
METHOD
We conducted structured clinical interviews with 74 children and adolescents with full or sub threshold ARFID to assess the presence of comorbid psychiatric diagnoses, suicidality, and the severity of each of the three ARFID profiles.
RESULTS
Nearly half of the sample (45%) met criteria for a current comorbid psychiatric diagnosis, and over half (53%) met criteria for a lifetime comorbid diagnosis. A total of 8% endorsed current suicidality and 14% endorsed lifetime suicidality. Severity in the sensory sensitivity profile was uniquely associated with greater odds of comorbid disorders in the neurodevelopmental, disruptive, and conduct disorders category; the anxiety, obsessive-compulsive, and trauma-related disorders category; and the depressive and bipolar-related disorders category. Severity in the fear of aversive consequences profile was associated with greater odds of disorders in the anxiety, obsessive-compulsive, and trauma-related disorders category.
DISCUSSION
Our findings underscore the severity of psychopathology among individuals with ARFID and related presentations, and also highlight the potential that shared psychopathology between specific ARFID profiles and other psychiatric disorders represent transdiagnostic constructs (e.g., avoidant behavior) that may be relevant treatment targets.
We aimed to characterize the current and lifetime prevalence of comorbid psychiatric diagnoses and suicidality in treatment- and nontreatment-seeking individuals with full and subthreshold avoidant/restrictive food intake disorder (ARFID). We also sought to examine unique associations between the three DSM-5 ARFID profiles (i.e., sensory sensitivity, fear of aversive consequences, and lack of interest in food or eating) and specific categories of psychiatric diagnoses and suicidality.
METHOD
We conducted structured clinical interviews with 74 children and adolescents with full or sub threshold ARFID to assess the presence of comorbid psychiatric diagnoses, suicidality, and the severity of each of the three ARFID profiles.
RESULTS
Nearly half of the sample (45%) met criteria for a current comorbid psychiatric diagnosis, and over half (53%) met criteria for a lifetime comorbid diagnosis. A total of 8% endorsed current suicidality and 14% endorsed lifetime suicidality. Severity in the sensory sensitivity profile was uniquely associated with greater odds of comorbid disorders in the neurodevelopmental, disruptive, and conduct disorders category; the anxiety, obsessive-compulsive, and trauma-related disorders category; and the depressive and bipolar-related disorders category. Severity in the fear of aversive consequences profile was associated with greater odds of disorders in the anxiety, obsessive-compulsive, and trauma-related disorders category.
DISCUSSION
Our findings underscore the severity of psychopathology among individuals with ARFID and related presentations, and also highlight the potential that shared psychopathology between specific ARFID profiles and other psychiatric disorders represent transdiagnostic constructs (e.g., avoidant behavior) that may be relevant treatment targets.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1002/eat.23191
- PMID 31702051
- Persistent URL
- https://sonar.ch/global/documents/170842
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