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Retrospective study on necrotizing enteritis in piglets in Switzerland.

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  • 2009-08-05
Published in:
  • Schweizer Archiv fur Tierheilkunde. - 2009
Animals
Animals, Newborn
Bacterial Toxins
Clostridium Infections
Clostridium perfringens
DNA, Bacterial
Disease Outbreaks
Enteritis
Enterotoxins
Female
Genotype
Male
Necrosis
Retrospective Studies
Swine
Swine Diseases
Switzerland
English The re-emergence of necrotizing enteritis (NE) in Swiss pig breeding farms raised concern that, besides C. perfringens type C strains, additional C. perfringens toxinotypes might cause this disease. Therefore we retrospectively investigated the association of NE with C. perfringens type C or different C. perfringens toxinotypes. We evaluated pathological lesions, routine diagnostic bacteriology results, and multiplex real-time PCR analyses from DNA extracts of archived intestinal samples of 199 piglets from our diagnostic case load. 96.5% of NE cases and 100% of herds affected by NE were positive for C. perfringens type C genotypes. Animals without necrotizing enteritis revealed a significantly lower detection rate of type C genotypes. Non affected piglets showed a high prevalence for beta-2-toxin positive C. perfringens type A strains. Collectively, our data indicate that outbreaks of NE in piglets in Switzerland cannot be attributed to newly emerging pathogenic toxinotypes, but are due to a spread of pathogenic C. perfringens type C strains.
Language
  • English
Open access status
green
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Persistent URL
https://sonar.ch/global/documents/172624
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