Oscillating circuitries in the sleeping brain.

Adamantidis AR; Gutierrez Herrera C; Gent TC

doi:10.1038/s41583-019-0223-4

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Journal article

Oscillating circuitries in the sleeping brain.

Adamantidis AR Centre for Experimental Neurology, Department of Neurology, Inselspital University Hospital Bern, University of Bern, Bern, Switzerland. antoine.adamantidis@dbmr.unibe.ch.
Gutierrez Herrera C Centre for Experimental Neurology, Department of Neurology, Inselspital University Hospital Bern, University of Bern, Bern, Switzerland.
Gent TC Centre for Experimental Neurology, Department of Neurology, Inselspital University Hospital Bern, University of Bern, Bern, Switzerland.

2019-10-17

Published in:

Nature reviews. Neuroscience. - 2019

English Brain activity during sleep is characterized by circuit-specific oscillations, including slow waves, spindles and theta waves, which are nested in thalamocortical or hippocampal networks. A major challenge is to determine the relationships between these oscillatory activities and the identified networks of sleep-promoting and wake-promoting neurons distributed throughout the brain. Improved understanding of the neurobiological mechanisms that orchestrate sleep-related oscillatory activities, both in time and space, is expected to generate further insight into the delineation of sleep states and their functions.

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