Journal article
SIADH consecutive to ciprofloxacin intake.
- Adler D Internal Medicine Department, University Hospital of Geneva, Rue Micheli-du-Crest 24, 1211 Geneva 14, Switzerland.
- Voide C
- Thorens JB
- Desmeules J
- 2004-12-08
Published in:
- European journal of internal medicine. - 2004
English
The syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is often drug-induced. We describe the first case, to our knowledge, of SIADH consecutive to ciprofloxacin administration. On two occasions, a 70-year-old patient, known for post-actinic bladder with repeated episodes of hematuria, was given ciprofloxacin and developed severe hyponatremia with seizures. On both occasions, the patient's condition improved rapidly after withdrawal of the drug. As all organic diseases likely to cause SIADH were excluded, and because the drug rechallenge was positive, we suggest that ciprofloxacin be added to the list of drugs prone to induce SIADH.
- Language
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- English
- Open access status
- closed
- Identifiers
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- DOI 10.1016/j.ejim.2004.08.003
- PMID 15581752
- Persistent URL
- https://sonar.ch/global/documents/175346
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