Access to macrocycles with an endo aryl ether and an endo aryl-aryl bond, development and application.

Wang Q; Zhu J

doi:10.2533/chimia.2011.168

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Journal article

Access to macrocycles with an endo aryl ether and an endo aryl-aryl bond, development and application.

Wang Q Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne, Switzerland.
Zhu J

2011-05-03

Published in:

Chimia. - 2011

Complement Pathway, Alternative

English Macrocyclization methodologies allowing access to macrocycles having an endo aryl ether and an endo aryl-aryl bond, especially those based on an intramolecular S(N)Ar reaction and the Suzuki-Miyaura reaction, are summarized. Total synthesis of complestatin, a bis-macrocyclic natural product, featuring these two technologies are presented.

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