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Predictors of Outcomes Following Transcatheter Edge-to-Edge Mitral Valve Repair.
Journal article

Predictors of Outcomes Following Transcatheter Edge-to-Edge Mitral Valve Repair.

  • Ben-Shoshan J McGill University Health Center, McGill University, Montreal, Quebec, Canada; Tel-Aviv Medical Center, Tel-Aviv University, Tel-Aviv, Israel.
  • Overtchook P McGill University Health Center, McGill University, Montreal, Quebec, Canada; Bern University Hospital, University of Bern, Bern, Switzerland.
  • Buithieu J McGill University Health Center, McGill University, Montreal, Quebec, Canada.
  • Mousavi N McGill University Health Center, McGill University, Montreal, Quebec, Canada.
  • Martucci G McGill University Health Center, McGill University, Montreal, Quebec, Canada.
  • Spaziano M McGill University Health Center, McGill University, Montreal, Quebec, Canada.
  • de Varennes B McGill University Health Center, McGill University, Montreal, Quebec, Canada.
  • Lachapelle K McGill University Health Center, McGill University, Montreal, Quebec, Canada.
  • Brophy J McGill University Health Center, McGill University, Montreal, Quebec, Canada.
  • Modine T Centre Hospitalier Regional et Universitaire de Lille, Lille, France.
  • Baumbach A Barts Heart Centre, Barts Health NHS, Queen Mary University, London, United Kingdom.
  • Maisano F University Hospital of Zurich, University of Zurich, Zurich, Switzerland.
  • Prendergast B St. Thomas' Hospital, London, United Kingdom.
  • Tamburino C Ferrarotto Hospital, University of Catania, Catania, Italy.
  • Windecker S Bern University Hospital, University of Bern, Bern, Switzerland.
  • Piazza N McGill University Health Center, McGill University, Montreal, Quebec, Canada. Electronic address: nicolopiazza@mac.com.
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  • 2020-08-09
Published in:
  • JACC. Cardiovascular interventions. - 2020
English Transcatheter edge-to-edge mitral valve repair is a viable alternative to surgery in patients with severe mitral regurgitation and high surgical risk. Yet the specific group of patients who would optimally benefit from this therapy remains to be determined. Selection of patients for transcatheter strategy is currently based on surgical prognostic scores and technical feasibility. Meanwhile, various clinical, anatomic, and procedural factors have been recently recognized as predictors of adverse outcomes following transcatheter edge-to-edge mitral valve repair, including device failure, recurrent mitral regurgitation, and mortality. Integration of these prognostic factors in the decision-making process of the heart team might improve patient management and outcomes. Herein, the authors review the different factors related to symptomatic status, comorbidity, serum biomarkers, echocardiographic findings, and procedural technique that have been identified as independent predictors of adverse outcome following transcatheter edge-to-edge mitral valve repair and discuss their potential application in everyday clinical practice.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://sonar.ch/global/documents/178189
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