Journal article
History of hadron therapy accelerators.
- Degiovanni A CERN, BE-RF-MK L19900, CH-1211 Geneva 23, Switzerland. Electronic address: alberto.degiovanni@cern.ch.
- Amaldi U TERA Foundation, Via Puccini 11, 28100 Novara, Italy. Electronic address: ugo.amaldi@cern.ch.
- 2015-03-28
Published in:
- Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB). - 2015
Cyclotrons
Hadron therapy
Linacs
Medical accelerators
Particle therapy
Synchrotrons
Elementary Particles
History, 20th Century
History, 21st Century
Humans
Laboratories
Particle Accelerators
Physics
Radiotherapy
English
In the last 60 years, hadron therapy has made great advances passing from a stage of pure research to a well-established treatment modality for solid tumours. In this paper the history of hadron therapy accelerators is reviewed, starting from the first cyclotrons used in the thirties for neutron therapy and passing to more modern and flexible machines used nowadays. The technical developments have been accompanied by clinical studies that allowed the selection of the tumours which are more sensitive to this type of radiotherapy. This paper aims at giving a review of the origin and the present status of hadron therapy accelerators, describing the technological basis and the continuous development of this application to medicine of instruments developed for fundamental science. At the end the present challenges are reviewed.
- Language
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- English
- Open access status
- closed
- Identifiers
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- DOI 10.1016/j.ejmp.2015.03.002
- PMID 25812487
- Persistent URL
- https://sonar.ch/global/documents/180812
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