DNA profiling of tumor buds in colorectal cancer indicates that they have the same mutation profile as the tumor from which they derive.

• Centeno I Institute of Pathology, University of Bern, Murtenstrasse 31, Room L310, CH-3008, Bern, Switzerland.
• Paasinen Sohns A Institute of Pathology, Kantonsspital Baselland, Mühlemattstrasse 11, CH-4410, Liestal, Switzerland.
• Flury M Institute of Pathology, University of Bern, Murtenstrasse 31, Room L310, CH-3008, Bern, Switzerland.
• Galván JA Institute of Pathology, University of Bern, Murtenstrasse 31, Room L310, CH-3008, Bern, Switzerland.
• Zahnd S Institute of Pathology, University of Bern, Murtenstrasse 31, Room L310, CH-3008, Bern, Switzerland.
• Koelzer VH Institute of Pathology, University of Bern, Murtenstrasse 31, Room L310, CH-3008, Bern, Switzerland.
• Sokol L Institute of Pathology, University of Bern, Murtenstrasse 31, Room L310, CH-3008, Bern, Switzerland.
• Dawson HE Institute of Pathology, University of Bern, Murtenstrasse 31, Room L310, CH-3008, Bern, Switzerland.
• Lugli A Institute of Pathology, University of Bern, Murtenstrasse 31, Room L310, CH-3008, Bern, Switzerland.
• Cathomas G Institute of Pathology, Kantonsspital Baselland, Mühlemattstrasse 11, CH-4410, Liestal, Switzerland.
• Zlobec I Institute of Pathology, University of Bern, Murtenstrasse 31, Room L310, CH-3008, Bern, Switzerland. inti.zlobec@pathology.unibe.ch.

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Colorectal Neoplasms

DNA Mutational Analysis

Gene Expression Profiling

Humans

Mutation

Proto-Oncogene Proteins B-raf

Proto-Oncogene Proteins p21(ras)