Journal article
High-attenuation artifact reduction in breast tomosynthesis using a novel reconstruction algorithm.
- Dustler M Diagnostic Radiology, Department of Translational Medicine, Lund University, Sweden; Medical Radiation Physics Malmö, Department of Translational Medicine, Lund University, Sweden. Electronic address: magnus.dustler@med.lu.se.
- Wicklein J Siemens Healthcare GmbH, Forchheim, Germany.
- Förnvik H Medical Radiation Physics Malmö, Department of Translational Medicine, Lund University, Sweden; Radiation Physics, Department of Hematology, Oncology and Radiation Physics, Skåne University Hospital, Sweden.
- Boita J Department of Radiology and Nuclear Medicine, Radboud University Medical Centre, Nijmegen, the Netherlands; Dutch Expert Centre for Screening (LRCB), Nijmegen, the Netherlands.
- Bakic P X-ray Physics Lab, Department of Radiology, University of Pennsylvania, USA.
- Lång K Institute for Biomedical Engineering, ETH Zurich, Zurich, Switzerland.
- 2019-06-03
Published in:
- European journal of radiology. - 2019
Artifact reduction
Breast imaging
Breast tomosynthesis
Image reconstruction
Mammography
Algorithms
Artifacts
Biopsy
Breast
Breast Neoplasms
Female
Humans
Image Processing, Computer-Assisted
Mammography
Mastectomy
Metals
English
PURPOSE
To assess the effect on reducing the out-of-plane artifacts from metal objects in breast tomosynthesis (BT) using a novel artifact-reducing reconstruction algorithm in specimen radiography.
METHODS AND MATERIALS
The study was approved by the Regional Ethical Review Board. BT images of 18 partial- and whole mastectomy specimens from women with breast cancer were acquired before and after a needle was inserted close to the lesion. The images were reconstructed using both a standard reconstruction algorithm, and a novel algorithm; the latter uses pre-segmentation to remove highly attenuating artifact-inducing objects from projection images before reconstruction. Images were separately reconstructed with and without segmentation, and combined into an artifact-reduced reconstruction. Standard and artifact-reduced BT-algorithms were compared visually and quantitatively using clinical images of mastectomy specimens and a physical anthropomorphic phantom. Six readers independently assessed the visibility of the lesion with and without artifact-reduction in a side-by-side comparison. A quantitative analysis was performed, comparing the signal-difference to background ratio (SDBR) and artifact spread function (ASF) between the two reconstruction methods.
RESULTS
The magnitude of out-of-plane artifacts was clearly reduced with the novel reconstruction compared to BT-images without artifact reduction. Lesion masking by artifacts was largely averted; tumour visibility was comparable to standard BT images without a needle. In 76 ± 8% (standard deviation) of cases overall, readers could confidently state needle location. The same figure was 94 ± 6% for whole mastectomy cases, compared to 62 ± 17% for partial mastectomies. With metal artifact reduction, SDBR increased by 97% in the phantom, and by 69% in the mastectomies. The artifact spread function was substantially narrower.
CONCLUSION
Artifact reduction in BT using a novel reconstruction method enables qualitatively and quantitatively improved clinical use of BT when metal artifacts can be a limiting factor such as in tomosynthesis-guided biopsy.
To assess the effect on reducing the out-of-plane artifacts from metal objects in breast tomosynthesis (BT) using a novel artifact-reducing reconstruction algorithm in specimen radiography.
METHODS AND MATERIALS
The study was approved by the Regional Ethical Review Board. BT images of 18 partial- and whole mastectomy specimens from women with breast cancer were acquired before and after a needle was inserted close to the lesion. The images were reconstructed using both a standard reconstruction algorithm, and a novel algorithm; the latter uses pre-segmentation to remove highly attenuating artifact-inducing objects from projection images before reconstruction. Images were separately reconstructed with and without segmentation, and combined into an artifact-reduced reconstruction. Standard and artifact-reduced BT-algorithms were compared visually and quantitatively using clinical images of mastectomy specimens and a physical anthropomorphic phantom. Six readers independently assessed the visibility of the lesion with and without artifact-reduction in a side-by-side comparison. A quantitative analysis was performed, comparing the signal-difference to background ratio (SDBR) and artifact spread function (ASF) between the two reconstruction methods.
RESULTS
The magnitude of out-of-plane artifacts was clearly reduced with the novel reconstruction compared to BT-images without artifact reduction. Lesion masking by artifacts was largely averted; tumour visibility was comparable to standard BT images without a needle. In 76 ± 8% (standard deviation) of cases overall, readers could confidently state needle location. The same figure was 94 ± 6% for whole mastectomy cases, compared to 62 ± 17% for partial mastectomies. With metal artifact reduction, SDBR increased by 97% in the phantom, and by 69% in the mastectomies. The artifact spread function was substantially narrower.
CONCLUSION
Artifact reduction in BT using a novel reconstruction method enables qualitatively and quantitatively improved clinical use of BT when metal artifacts can be a limiting factor such as in tomosynthesis-guided biopsy.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1016/j.ejrad.2019.04.014
- PMID 31153567
- Persistent URL
- https://sonar.ch/global/documents/185169
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