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Comparative in vitro activity of Ro 40-6890, Ro 41-3399, and other antimicrobial agents against anaerobic bacteria.
Journal article

Comparative in vitro activity of Ro 40-6890, Ro 41-3399, and other antimicrobial agents against anaerobic bacteria.

  • Wüst J Department of Medical Microbiology, University of Zurich, Switzerland.
  • Hardegger U
  • 1992-10-01
Published in:
  • European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology. - 1992
Amoxicillin
Bacteria, Anaerobic
Bacteroides
Bacteroides fragilis
Cephalosporins
Chloramphenicol
Clindamycin
Clostridium perfringens
Metronidazole
Microbial Sensitivity Tests
English The in vitro activity of the ester Ro 41-3399 and its free active acid Ro 40-6890 was tested against 189 strains of anaerobic bacteria in comparison to other oral cephalosporins and to antimicrobial agents established in the treatment of anaerobic infections. Prevotella, Porphyromonas, Peptostreptococcus, Fusobacterium and Clostridium spp. were susceptible to Ro 40-6890, with few exceptions. Due to its lack of activity against the major pathogens of the Bacteriodes fragilis group, Ro 40-6890 does not promise to be of major use in the treatment of infections caused by anaerobes.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://sonar.ch/global/documents/185380
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