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An evaluation of the relationship between 'atopic skin' and skin irritability in metalworker trainees.
Journal article

An evaluation of the relationship between 'atopic skin' and skin irritability in metalworker trainees.

  • 1997-06-01
Published in:
  • Contact dermatitis. - 1997
Adolescent
Adult
Dermatitis, Atopic
Dermatitis, Contact
Dermatitis, Irritant
Dermatitis, Occupational
Dimethyl Sulfoxide
Drug Hypersensitivity
Evaluation Studies as Topic
Humans
Male
Metallurgy
Multivariate Analysis
Regression Analysis
Skin Tests
Sodium Dodecyl Sulfate
Sodium Hydroxide
Switzerland
Water Loss, Insensible
English Skin hyperirritability to irritants as well as atopy are considered to be predisposing factors for contact dermatitis. The aim of the study was to evaluate whether these predictive factors are independent or whether they are so closely related that one could possibly replace the other 205 metalworker trainees underwent skin examination for skin atopy, including standardized questionnaire, clinical examination of the skin and a series of skin irritability tests. These tests included measurements of transepidermal water loss (TEWL) before and after irritation with 3 different irritants: sodium lauryl sulfate (SLS), dimethylsulfoxide (DMSO) and sodium hydroxide (NaOH). The results of the linear regression analysis demonstrate that skin atopy is not associated with increased skin irritability, as assessed by the irritability testing methods presented.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://sonar.ch/global/documents/185645
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