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The MADS-box transcription factor PHERES1 controls imprinting in the endosperm by binding to domesticated transposons
Journal article

The MADS-box transcription factor PHERES1 controls imprinting in the endosperm by binding to domesticated transposons

  • Batista, Rita A ORCID Linnean Centre for Plant Biology, Swedish University of Agricultural Sciences, Uppsala, Sweden
  • Moreno-Romero, Jordi Linnean Centre for Plant Biology, Swedish University of Agricultural Sciences, Uppsala, Sweden
  • Qiu, Yichun Linnean Centre for Plant Biology, Swedish University of Agricultural Sciences, Uppsala, Sweden
  • van Boven, Joram Linnean Centre for Plant Biology, Swedish University of Agricultural Sciences, Uppsala, Sweden
  • Santos-González, Juan Linnean Centre for Plant Biology, Swedish University of Agricultural Sciences, Uppsala, Sweden
  • Figueiredo, Duarte D ORCID Linnean Centre for Plant Biology, Swedish University of Agricultural Sciences, Uppsala, Sweden
  • Köhler, Claudia ORCID Linnean Centre for Plant Biology, Swedish University of Agricultural Sciences, Uppsala, Sweden
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  • 2019-12-2
Published in:
  • eLife. - eLife Sciences Publications, Ltd. - 2019, vol. 8
General Biochemistry, Genetics and Molecular Biology
General Immunology and Microbiology
General Neuroscience
General Medicine
English MADS-box transcription factors (TFs) are ubiquitous in eukaryotic organisms and play major roles during plant development. Nevertheless, their function in seed development remains largely unknown. Here, we show that the imprinted Arabidopsis thaliana MADS-box TF PHERES1 (PHE1) is a master regulator of paternally expressed imprinted genes, as well as of non-imprinted key regulators of endosperm development. PHE1 binding sites show distinct epigenetic modifications on maternal and paternal alleles, correlating with parental-specific transcriptional activity. Importantly, we show that the CArG-box-like DNA-binding motifs that are bound by PHE1 have been distributed by RC/Helitron transposable elements. Our data provide an example of the molecular domestication of these elements which, by distributing PHE1 binding sites throughout the genome, have facilitated the recruitment of crucial endosperm regulators into a single transcriptional network.
Language
  • English
Open access status
gold
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Persistent URL
https://sonar.ch/global/documents/186354
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