Lipid and Carbohydrate Metabolism in Caenorhabditis elegans.
Journal article

Lipid and Carbohydrate Metabolism in Caenorhabditis elegans.

  • Watts JL School of Molecular Biosciences and Center for Reproductive Biology, Washington State University, Pullman, Washington 99164 jwatts@vetmed.wsu.edu.
  • Ristow M Energy Metabolism Laboratory, Institute of Translational Medicine, Department of Health Sciences and Technology, Swiss Federal Institute of Technology Zurich, 8603 Schwerzenbach-Zurich, Switzerland.
  • 2017-10-06
Published in:
  • Genetics. - 2017
English Lipid and carbohydrate metabolism are highly conserved processes that affect nearly all aspects of organismal biology. Caenorhabditis elegans eat bacteria, which consist of lipids, carbohydrates, and proteins that are broken down during digestion into fatty acids, simple sugars, and amino acid precursors. With these nutrients, C. elegans synthesizes a wide range of metabolites that are required for development and behavior. In this review, we outline lipid and carbohydrate structures as well as biosynthesis and breakdown pathways that have been characterized in C. elegans We bring attention to functional studies using mutant strains that reveal physiological roles for specific lipids and carbohydrates during development, aging, and adaptation to changing environmental conditions.
Language
  • English
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https://sonar.ch/global/documents/188278
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