Journal article
The role of chromatin in HIV-1 transcriptional regulation.
- Mirkovitch J Swiss Institute for Experimental Cancer Research (ISREC), Epalinges, Switzerland. jmirkovi@isrec.unil.ch
- 1998-01-27
Published in:
- Immunobiology. - 1997
Animals
Chromatin
DNA Footprinting
Deoxyribonuclease I
Forecasting
Gene Expression Regulation, Viral
Gene Products, tat
HIV Long Terminal Repeat
HIV-1
Humans
Nucleosomes
Peptide Chain Elongation, Translational
Proteins
Regulatory Sequences, Nucleic Acid
Transcription Factors
Transcription, Genetic
tat Gene Products, Human Immunodeficiency Virus
English
Regulation of transcription is a key feature of the HIV-1 life cycle. In recent years, various sequence elements and transcription factors have been shown to participate in HIV-1 transcription control. New evidence, however, has shown that chromatin organization plays a key role in the establishment of a transcriptionally regulated HIV-1 LTR. The present review discusses recent data obtained on reconstituted and genomic HIV-1 chromatin templates.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1016/S0171-2985(97)80048-4
- PMID 9442399
- Persistent URL
- https://sonar.ch/global/documents/189419
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