Gönczy PISREC (Swiss Institute for Experimental Cancer Research), 155, ch. des Boveresses, CH-1066, Epalinges/Lausanne, Switzerland. Pierre.Gonczy@isrec.unil.ch
English
The findings of two recent studies suggest a novel mechanism for nuclear envelope breakdown in which cytoplasmic dynein anchored on the outside of the nucleus generates tension, thus triggering tearing of the nuclear envelope.