Back
Five new prenylated stilbenes from the root bark of Lonchocarpus chiricanus.
Journal article

Five new prenylated stilbenes from the root bark of Lonchocarpus chiricanus.

  • 2001-06-26
Published in:
  • Journal of natural products. - 2001
Aedes
Animals
Antifungal Agents
Chromatography, High Pressure Liquid
Cladosporium
Fabaceae
Insecticides
Larva
Magnetic Resonance Spectroscopy
Microbial Sensitivity Tests
Panama
Plant Epidermis
Plants, Medicinal
Protein Prenylation
Spectrophotometry, Ultraviolet
Stilbenes
English Besides the known compounds longistylines C (1), D (2), and 3,5-dimethoxystilbene (5), five new prenylated stilbenes, named chiricanines A--E (3, 4, 6--8), have been isolated from the root bark of Lonchocarpus chiricanus. Their structures were resolved on the basis of spectrometric methods including (1)H, (13)C, and 2D NMR experiments and mass spectrometry. Compound 3 was the only prenylated stilbene to demonstrate antifungal effects against Cladosporium cucumerinum. Four of the isolated compounds showed toxic properties against larvae of the yellow fever-transmitting mosquito Aedes aegypti. Compound 5 was found to be as potent as rotenone in larvicidal dilution tests.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://sonar.ch/global/documents/189560
Statistics
Document views: 41 File downloads: