Journal article
Clinical application of MOSkin dosimeters to rectal wall in vivo dosimetry in gynecological HDR brachytherapy.
- Carrara M Medical Physics Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy. Electronic address: Mauro.Carrara@eoc.ch.
- Romanyukha A Centre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW, Australia.
- Tenconi C Medical Physics Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.
- Mazzeo D Department of Physics, Università degli Studi di Milano, and INFN, Milan, Italy.
- Cerrotta A Radiation Oncology 2 Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.
- Borroni M Medical Physics Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.
- Cutajar D Centre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW, Australia.
- Petasecca M Centre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW, Australia.
- Lerch M Centre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW, Australia.
- Bucci J St George Cancer Care Center, Kogarah, NSW, Australia.
- Richetti A Radiation Oncology Unit, Ente Ospedaliero Cantonale, Bellinzona, Switzerland.
- Presilla S Medical Physics Unit, Ente Ospedaliero Cantonale, Bellinzona, Switzerland.
- Fallai C Radiation Oncology 2 Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.
- Gambarini G Department of Physics, Università degli Studi di Milano, and INFN, Milan, Italy.
- Pignoli E Medical Physics Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.
- Rosenfeld A Centre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW, Australia.
- 2017-05-14
Published in:
- Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB). - 2017
HDR brachytherapy
In vivo dosimetry
Solid state dosimetry
Vaginal cancer
Brachytherapy
Female
Humans
In Vivo Dosimetry
Radiation Dosimeters
Radiometry
Radiotherapy Dosage
Rectum
Vaginal Neoplasms
English
PURPOSE
Three MOSkins dosimeters were assembled over a rectal probe and used to perform in vivo dosimetry during HDR brachytherapy treatments of vaginal cancer. The purpose of this study was to verify the applicability of the developed tool to evaluate discrepancies between planned and measured doses to the rectal wall.
MATERIALS AND METHODS
MOSkin dosimeters from the Centre for Medical Radiation Physics are particularly suitable for brachytherapy procedures for their ability to be easily incorporated into treatment instrumentation. In this study, 26 treatment sessions of HDR vaginal brachytherapy were monitored using three MOSkin mounted on a rectal probe. A total of 78 measurements were collected and compared to doses determined by the treatment planning system.
RESULTS
Mean dose discrepancy was determined as 2.2±6.9%, with 44.6% of the measurements within ±5%, 89.2% within ±10% and 10.8% higher than ±10%. When dose discrepancies were grouped according to the time elapsed between imaging and treatment (i.e., group 1: ≤90min; group 2: >90min), mean discrepancies resulted in 4.7±3.6% and 7.1±5.0% for groups 1 and 2, respectively. Furthermore, the position of the dosimeter on the rectal catheter was found to affect uncertainty, where highest uncertainties were observed for the dosimeter furthest inside the rectum.
CONCLUSIONS
This study has verified MOSkin applicability to in-patient dose monitoring in gynecological brachytherapy procedures, demonstrating the dosimetric rectal probe setup as an accurate and convenient IVD instrument for rectal wall dose verification. Furthermore, the study demonstrates that the delivered dose discrepancy may be affected by the duration of treatment planning.
Three MOSkins dosimeters were assembled over a rectal probe and used to perform in vivo dosimetry during HDR brachytherapy treatments of vaginal cancer. The purpose of this study was to verify the applicability of the developed tool to evaluate discrepancies between planned and measured doses to the rectal wall.
MATERIALS AND METHODS
MOSkin dosimeters from the Centre for Medical Radiation Physics are particularly suitable for brachytherapy procedures for their ability to be easily incorporated into treatment instrumentation. In this study, 26 treatment sessions of HDR vaginal brachytherapy were monitored using three MOSkin mounted on a rectal probe. A total of 78 measurements were collected and compared to doses determined by the treatment planning system.
RESULTS
Mean dose discrepancy was determined as 2.2±6.9%, with 44.6% of the measurements within ±5%, 89.2% within ±10% and 10.8% higher than ±10%. When dose discrepancies were grouped according to the time elapsed between imaging and treatment (i.e., group 1: ≤90min; group 2: >90min), mean discrepancies resulted in 4.7±3.6% and 7.1±5.0% for groups 1 and 2, respectively. Furthermore, the position of the dosimeter on the rectal catheter was found to affect uncertainty, where highest uncertainties were observed for the dosimeter furthest inside the rectum.
CONCLUSIONS
This study has verified MOSkin applicability to in-patient dose monitoring in gynecological brachytherapy procedures, demonstrating the dosimetric rectal probe setup as an accurate and convenient IVD instrument for rectal wall dose verification. Furthermore, the study demonstrates that the delivered dose discrepancy may be affected by the duration of treatment planning.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1016/j.ejmp.2017.05.003
- PMID 28499627
- Persistent URL
- https://sonar.ch/global/documents/190066
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