Journal article
In Vivo Molecular Bioluminescence Imaging: New Tools and Applications.
-
Mezzanotte L
Optical Molecular imaging, Department of Radiology, Erasmus MC, Rotterdam, The Netherlands. Electronic address: l.mezzanotte@erasmusmc.nl.
-
van 't Root M
Optical Molecular imaging, Department of Radiology, Erasmus MC, Rotterdam, The Netherlands.
-
Karatas H
Laboratory of Bioorganic Chemistry and Molecular Imaging, Institute of Chemical Sciences and Engineering (ISIC), Swiss Federal Institute of Technology Lausanne (EPFL), 1015 Lausanne, Switzerland.
-
Goun EA
Laboratory of Bioorganic Chemistry and Molecular Imaging, Institute of Chemical Sciences and Engineering (ISIC), Swiss Federal Institute of Technology Lausanne (EPFL), 1015 Lausanne, Switzerland.
-
Löwik CWGM
Optical Molecular imaging, Department of Radiology, Erasmus MC, Rotterdam, The Netherlands.
Show more…
Published in:
- Trends in biotechnology. - 2017
English
in vivo bioluminescence imaging (BLi) is an optical molecular imaging technique used to visualize molecular and cellular processes in health and diseases and to follow the fate of cells with high sensitivity using luciferase-based gene reporters. The high sensitivity of this technique arises from efficient photon production, followed by the reaction between luciferase enzymes and luciferin substrates. Novel discoveries and developments of luciferase reporters, substrates, and gene-editing techniques, and emerging fields of applications, promise a new era of deeper and more sensitive molecular imaging.
-
Language
-
-
Open access status
-
closed
-
Identifiers
-
-
Persistent URL
-
https://sonar.ch/global/documents/190535
Statistics
Document views: 15
File downloads: