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A constraint on cAMP signaling.
Journal article

A constraint on cAMP signaling.

  • Mansuy I Institute of Cell Biology, ETH Honggerberg, Zurich, Switzerland.
  • 2004-01-13
Published in:
  • Neuron. - 2004
Adenylyl Cyclase Inhibitors
Animals
Cyclic AMP
GTP-Binding Protein alpha Subunits, Gi-Go
Hippocampus
Memory
Signal Transduction
English Studies in invertebrates and vertebrates have demonstrated a critical role for cAMP signaling and adenylyl cyclase (AC) activity in learning and memory. In this issue of Neuron, Pineda et al. show that in the hippocampus, reduction of AC activity via the inhibitory G protein G(i) is critical for memory formation, suggesting that a balance of inhibitory and stimulatory regulators of AC is required for optimal cAMP signaling.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://sonar.ch/global/documents/190942
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