RNA interference efficiently targets human leukemia driven by a fusion oncogene in vivo.

• Jyotsana N Department of Hematology, Hemostasis, Oncology and Stem cell Transplantation, Hannover Medical School, Hannover, Germany.
• Sharma A Department of Hematology, Hemostasis, Oncology and Stem cell Transplantation, Hannover Medical School, Hannover, Germany.
• Chaturvedi A Department of Hematology, Hemostasis, Oncology and Stem cell Transplantation, Hannover Medical School, Hannover, Germany.
• Scherr M Department of Hematology, Hemostasis, Oncology and Stem cell Transplantation, Hannover Medical School, Hannover, Germany.
• Kuchenbauer F Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany.
• Sajti L Nanotechnology Department, Laser Zentrum Hannover, Hannover, Germany.
• Barchanski A Nanotechnology Department, Laser Zentrum Hannover, Hannover, Germany.
• Lindner R Department of Cell Biology, Center of Anatomy, Hannover Medical School, Hannover, Germany.
• Noyan F Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.
• Sühs KW Clinic for Neurology, Hannover Medical School, Hannover, Germany.
• Grote-Koska D Department of Clinical Chemistry, Hannover Medical School, Hannover, Germany.
• Brand K Department of Clinical Chemistry, Hannover Medical School, Hannover, Germany.
• Vornlocher HP Axolabs GmBH, Kulmbach, Germany.
• Stanulla M Pediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany.
• Bornhauser B Department of Oncology and Children's Research Centre, University Children's Hospital Zürich, Zürich, Switzerland.
• Bourquin JP Department of Oncology and Children's Research Centre, University Children's Hospital Zürich, Zürich, Switzerland.
• Eder M Department of Hematology, Hemostasis, Oncology and Stem cell Transplantation, Hannover Medical School, Hannover, Germany.
• Thol F Department of Hematology, Hemostasis, Oncology and Stem cell Transplantation, Hannover Medical School, Hannover, Germany.
• Ganser A Department of Hematology, Hemostasis, Oncology and Stem cell Transplantation, Hannover Medical School, Hannover, Germany.
• Humphries RK Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, British Columbia, Canada.
• Ramsay E Precision NanoSystems, Inc., Vancouver, British Columbia, Canada.
• Cullis P Department of Biochemistry and Molecular Biology, University of British Columbia, Health Sciences Mall, Vancouver, British Columbia, Canada.
• Heuser M Department of Hematology, Hemostasis, Oncology and Stem cell Transplantation, Hannover Medical School, Hannover, Germany.

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Amyloid Neuropathies, Familial

Animals

B-Lymphocytes

Humans

Leukemia, B-Cell

Mice

Oncogene Proteins, Fusion

Precursor Cell Lymphoblastic Leukemia-Lymphoma

RNA Interference