Journal article
Increased Prevalence of Flammer Syndrome in Patients with Retinitis Pigmentosa.
- Konieczka K Department of Ophthalmology, University of Basel, Switzerland (Chairman ad interim: Prof. S. Orguel).
- Koch S Department of Ophthalmology, University of Basel, Switzerland (Chairman ad interim: Prof. S. Orguel).
- Schoetzau A Department of Ophthalmology, University of Basel, Switzerland (Chairman ad interim: Prof. S. Orguel).
- Todorova MG Department of Ophthalmology, University of Basel, Switzerland (Chairman ad interim: Prof. S. Orguel).
- 2016-04-27
Published in:
- Klinische Monatsblatter fur Augenheilkunde. - 2016
Adult
Aged
Causality
Comorbidity
Female
Humans
Male
Middle Aged
Peripheral Vascular Diseases
Prevalence
Retinitis Pigmentosa
Risk Factors
Sensation Disorders
Switzerland
Syndrome
English
BACKGROUND
"Retinitis pigmentosa" refers to a group of degenerative eye diseases with a genetic background. Flammer syndrome encompasses a set of symptoms and signs, mainly but not exclusively related to dysregulation of blood vessels. The purpose of the present study was to determine, with the help of a questionnaire, whether symptoms of Flammer syndrome occur more often in patients with retinitis pigmentosa than in controls.
METHODS
76 patients with retinitis pigmentosa (members of the Swiss patient organization for retinitis pigmentosa) and 274 control subjects answered a questionnaire (Flammer Syndrome Questionnaire) on 15 symptoms and signs of Flammer syndrome.
RESULTS
Seven of 15 symptoms and signs of Flammer syndrome were significantly more often positive in retinitis pigmentosa patients than in controls. Six additional symptoms and signs occurred non-significantly more often and 2 non-significantly less often in patients with retinitis pigmentosa.
CONCLUSION
Retinitis pigmentosa patients suffer significantly more often from symptoms and signs of the Flammer syndrome than control subjects. This includes low body mass index, low blood pressure, feeling cold, migraine, increased smell perception and perfectionism. The reason for this association between retinitis pigmentosa and Flammer syndrome and the potential implications need to be determined.
"Retinitis pigmentosa" refers to a group of degenerative eye diseases with a genetic background. Flammer syndrome encompasses a set of symptoms and signs, mainly but not exclusively related to dysregulation of blood vessels. The purpose of the present study was to determine, with the help of a questionnaire, whether symptoms of Flammer syndrome occur more often in patients with retinitis pigmentosa than in controls.
METHODS
76 patients with retinitis pigmentosa (members of the Swiss patient organization for retinitis pigmentosa) and 274 control subjects answered a questionnaire (Flammer Syndrome Questionnaire) on 15 symptoms and signs of Flammer syndrome.
RESULTS
Seven of 15 symptoms and signs of Flammer syndrome were significantly more often positive in retinitis pigmentosa patients than in controls. Six additional symptoms and signs occurred non-significantly more often and 2 non-significantly less often in patients with retinitis pigmentosa.
CONCLUSION
Retinitis pigmentosa patients suffer significantly more often from symptoms and signs of the Flammer syndrome than control subjects. This includes low body mass index, low blood pressure, feeling cold, migraine, increased smell perception and perfectionism. The reason for this association between retinitis pigmentosa and Flammer syndrome and the potential implications need to be determined.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1055/s-0041-111802
- PMID 27116506
- Persistent URL
- https://sonar.ch/global/documents/195058
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