Journal article
NDR kinases regulate essential cell processes from yeast to humans.
- Hergovich A Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, CH-4058 Basel, Switzerland.
- Stegert MR
- Schmitz D
- Hemmings BA
- 2006-04-12
Published in:
- Nature reviews. Molecular cell biology. - 2006
Animals
Apoptosis
Cell Proliferation
Gene Expression Regulation, Enzymologic
Humans
Mitosis
Neurons
Protein-Serine-Threonine Kinases
Saccharomyces cerevisiae
English
Members of the NDR (nuclear Dbf2-related) protein-kinase family are essential components of pathways that control important cellular processes, such as morphological changes, mitotic exit, cytokinesis, cell proliferation and apoptosis. Recent progress has shed light on the mechanisms that underlie the regulation and function of the NDR family members. Combined data from yeast, worms, flies, mice and human cells now highlight the conserved and important roles of the different NDR kinases in distinct cellular processes.
- Language
-
- English
- Open access status
- closed
- Identifiers
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- DOI 10.1038/nrm1891
- PMID 16607288
- Persistent URL
- https://sonar.ch/global/documents/198400
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