Coating and Functionalization Strategies for Nanogels and Nanoparticles for Selective Drug Delivery.
- Pinelli F Dipartimento di Chimica, Materiali e Ingegneria Chimica "Giulio Natta", Politecnico di Milano, via Mancinelli 7, 20131 Milan, Italy.
- Perale G Faculty of Biomedical Sciences, University of Southern Switzerland (USI), Via Buffi 13, 6900 Lugano, Switzerland.
- Rossi F Dipartimento di Chimica, Materiali e Ingegneria Chimica "Giulio Natta", Politecnico di Milano, via Mancinelli 7, 20131 Milan, Italy.
- 2020-02-09
Published in:
- Gels (Basel, Switzerland). - 2020
English
Drug delivery is a fascinating research field with several development opportunities. Great attention is now focused on colloidal systems, nanoparticles, and nanogels and on the possibility of modifying them in order to obtain precise targeted drug delivery systems. The aim of this review is to give an overview of the main available surface functionalization and coating strategies that can be adopted in order to modify the selectivity of the nanoparticles in the delivery process and obtain a final system with great targeted drug delivery ability. We also highlight the most important fields of application of these kinds of delivery systems and we propose a comparison between the advantages and disadvantages of the described functionalization strategies.
- Language
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- English
- Open access status
- gold
- Identifiers
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- DOI 10.3390/gels6010006
- PMID 32033057
- Persistent URL
- https://sonar.ch/global/documents/19883
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