Journal article
Fatal anaphylactic reaction to intravenous gadobutrol, a gadolinium-based MRI contrast agent.
- Franckenberg S Institute of Diagnostic and Interventional Radiology, University Hospital of Zurich, Raemistrasse 100, 8091 Zurich, Switzerland.
- Berger F Institute of Forensic Medicine, University of Zurich, 8057 Zurich, Switzerland.
- Schaerli S Institute of Forensic Medicine, University of Zurich, 8057 Zurich, Switzerland.
- Ampanozi G Institute of Forensic Medicine, University of Zurich, 8057 Zurich, Switzerland.
- Thali M Institute of Forensic Medicine, University of Zurich, 8057 Zurich, Switzerland.
- 2018-03-20
Published in:
- Radiology case reports. - 2018
English
We present the rare case of a fatal anaphylactic reaction to gadobutrol, a magnetic resonance imaging contrast agent, in a 42-year-old man. The patient underwent elective magnetic resonance imaging for diagnostic clarification of a suspicious finding in the abdomen. The patient had undergone contrast-enhanced computed tomography previously without the occurrence of any adverse effects. Adverse drug reactions in gadobutrol have a very low prevalence of 0.32%-3.5%, with serious adverse drug reactions in <0.1%. There are only a few cases of fatal anaphylactoid reactions to gadolinium-based contrast agents in general. However, if an anaphylactoid reaction occurs, it can present itself with a fulminant course within minutes.
- Language
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- English
- Open access status
- gold
- Identifiers
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- DOI 10.1016/j.radcr.2017.09.012
- PMID 29552267
- Persistent URL
- https://sonar.ch/global/documents/200079
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