Journal article
Glucagon-like peptide 1 (GLP-1) and eating.
- Gutzwiller JP Division of Gastroenterology, University Hospital, Basel, Switzerland.
- Degen L
- Heuss L
- Beglinger C
- 2004-07-06
Published in:
- Physiology & behavior. - 2004
Animals
Antibodies
Digestive System
Eating
Glucagon
Glucagon-Like Peptide 1
Glucagon-Like Peptide-1 Receptor
Humans
Peptide Fragments
Protein Precursors
Receptors, Glucagon
English
New information regarding gastrointestinal mechanisms that participate in the control of food intake has extended our understanding of appetite control. Although each new signaling pathway discovered in the gut is a potential target for drug development in the treatment of obesity, the growing number of such signaling molecules indicates that a highly complex process controls food intake. The present summary focuses on the role of glucagon-like peptide 1 (GLP-1) in this regulatory process. The different biological effects of GLP-1 (glucose-lowering properties, inhibition of appetite and food intake) provide a powerful impetus for development of GLP-1-based new drugs.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1016/j.physbeh.2004.04.019
- PMID 15234584
- Persistent URL
- https://sonar.ch/global/documents/205210
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