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Regulatory circuits in Caulobacter.
Journal article

Regulatory circuits in Caulobacter.

  • Osterås M Division of Molecular Microbiology, Biozentrum, University of Basel, Basel, CH-4056, Switzerland.
  • Jenal U
  • 2000-04-04
Published in:
  • Current opinion in microbiology. - 2000
Bacterial Proteins
Caulobacter crescentus
Cell Cycle
DNA-Binding Proteins
Enzyme Activation
Feedback
Phosphorylation
Protein Kinases
Time Factors
Transcription Factors
English The transcriptional regulator CtrA controls DNA replication, DNA methylation and cell division during the Caulobacter cell cycle. Recent work on this master cell cycle regulator has provided insight into its control mechanisms. Feedback regulation of ctrA transcription together with timed proteolysis of CtrA determine the levels of the regulator during the cell cycle. Multiple phosphorylation pathways regulate CtrA activity by a mechanism that includes dynamic subcellular localization of the corresponding sensor kinases.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://sonar.ch/global/documents/205229
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