No benefit of longer eradication therapy of Pseudomonas aeruginosa primoinfections in pediatric cystic fibrosis.
- Claude F Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland. fabien.claude@unil.ch.
- Rochat I Department of Pediatrics, Respiratory Unit, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
- Hafen GM Department of Pediatrics, Respiratory Unit, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
- 2019-03-06
Published in:
- BMC research notes. - 2019
Cystic fibrosis
Eradication protocol
Primoinfection
Pseudomonas aeruginosa
Anti-Bacterial Agents
Child
Ciprofloxacin
Clinical Protocols
Cystic Fibrosis
Female
Humans
Male
Outcome and Process Assessment, Health Care
Pseudomonas Infections
Pseudomonas aeruginosa
Retrospective Studies
Time Factors
Tobramycin
English
OBJECTIVE
Patients with cystic fibrosis are more susceptible than members of the general population to lung infections. Infections with Pseudomonas aeruginosa require particular attention, because they may accelerate the deterioration of lung function if not adequately treated. This study assessed the eradication rate of P. aeruginosa primoinfections, with a protocol of inhaled tobramycin and oral ciprofloxacin over a 3 months' period.
RESULTS
Retrospective single-center study from June 1st, 2007 to December 31st, 2015. Inclusion of 28 pediatric patients (11 females, 17 males), with a total of 49 primoinfections. Overall success rate of 67.3%, which is similar or even inferior to figures published in the literature.
Patients with cystic fibrosis are more susceptible than members of the general population to lung infections. Infections with Pseudomonas aeruginosa require particular attention, because they may accelerate the deterioration of lung function if not adequately treated. This study assessed the eradication rate of P. aeruginosa primoinfections, with a protocol of inhaled tobramycin and oral ciprofloxacin over a 3 months' period.
RESULTS
Retrospective single-center study from June 1st, 2007 to December 31st, 2015. Inclusion of 28 pediatric patients (11 females, 17 males), with a total of 49 primoinfections. Overall success rate of 67.3%, which is similar or even inferior to figures published in the literature.
- Language
-
- English
- Open access status
- gold
- Identifiers
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- DOI 10.1186/s13104-019-4157-8
- PMID 30832714
- Persistent URL
- https://sonar.ch/global/documents/20576
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