Cytokines and chemokines in irritant contact dermatitis.
- Lee HY Department of Dermatology, Inselspital, University of Bern, 3010 Bern, Switzerland.
- Stieger M Department of Dermatology, Inselspital, University of Bern, 3010 Bern, Switzerland.
- Yawalkar N Department of Dermatology, Inselspital, University of Bern, 3010 Bern, Switzerland.
- Kakeda M Department of Dermatology, Inselspital, University of Bern, 3010 Bern, Switzerland ; Department of Dermatology, Mie University Graduate School of Medicine, Tsu, Mie 514-8507, Japan.
- 2013-12-28
Published in:
- Mediators of inflammation. - 2013
Animals
Chemokines
Cytokines
Dendritic Cells
Dermatitis, Irritant
Endothelial Cells
Fibroblasts
Humans
Keratinocytes
Lymphocytes
English
Irritant contact dermatitis is a result of activated innate immune response to various external stimuli and consists of complex interplay which involves skin barrier disruption, cellular changes, and release of proinflammatory mediators. In this review, we will focus on key cytokines and chemokines involved in the pathogenesis of irritant contact dermatitis and also contrast the differences between allergic contact dermatitis and irritant contact dermatitis.
- Language
-
- English
- Open access status
- gold
- Identifiers
-
- DOI 10.1155/2013/916497
- PMID 24371376
- Persistent URL
- https://sonar.ch/global/documents/206460
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