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Spinal cord repair: advances in biology and technology.
Journal article

Spinal cord repair: advances in biology and technology.

  • Courtine G Center for Neuroprosthetics and Brain Mind Institute, School of Life Sciences, Swiss Federal Institute of Technology (EPFL), Geneva, Switzerland. gregoire.courtine@epfl.ch.
  • Sofroniew MV Department of Neurobiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
  • 2019-06-05
Published in:
  • Nature medicine. - 2019
Animals
Biocompatible Materials
Bioengineering
Disease Models, Animal
Humans
Models, Neurological
Neuronal Plasticity
Recovery of Function
Spinal Cord Injuries
Spinal Cord Regeneration
Translational Medical Research
English Individuals with spinal cord injury (SCI) can face decades with permanent disabilities. Advances in clinical management have decreased morbidity and improved outcomes, but no randomized clinical trial has demonstrated the efficacy of a repair strategy for improving recovery from SCI. Here, we summarize recent advances in biological and engineering strategies to augment neuroplasticity and/or functional recovery in animal models of SCI that are pushing toward clinical translation.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://sonar.ch/global/documents/209940
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