Journal article
Palmitoylation, pathogens and their host
- Blanc, Mathieu Global Health Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), Station 19, CH-1015 Lausanne, Switzerland
- Blaskovic, Sanja Global Health Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), Station 19, CH-1015 Lausanne, Switzerland
- van der Goot, F. Gisou Global Health Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), Station 19, CH-1015 Lausanne, Switzerland
- 2013-1-29
Published in:
- Biochemical Society Transactions. - Portland Press Ltd.. - 2013, vol. 41, no. 1, p. 84-88
English
S-Palmitoylation, the only reversible post-translational lipid modification, confers unique biochemical and functional properties to proteins. Although it has long been known that viral proteins are palmitoylated, recent studies reveal that this modification plays a critical role for pathogens of all kinds and at multiple steps of their life cycle. The present review examines the involvement of S-palmitoylation in infection by viruses, bacteria and parasites and illustrates how pathogens have evolved to manipulate the host palmitoylation machinery.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1042/bst20120337
- ISSN 0300-5127
- Persistent URL
- https://sonar.ch/global/documents/211488
Statistics
Document views: 26
File downloads: