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Palmitoylation, pathogens and their host.
Journal article

Palmitoylation, pathogens and their host.

  • Blanc M Global Health Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), Station 19, CH-1015 Lausanne, Switzerland. mathieu.blanc@epfl.ch
  • Blaskovic S
  • van der Goot FG
  • 2013-01-30
Published in:
  • Biochemical Society transactions. - 2013
Bacterial Physiological Phenomena
Fungi
Host-Pathogen Interactions
Lipoylation
Palmitic Acid
Viral Proteins
Virus Physiological Phenomena
English S-Palmitoylation, the only reversible post-translational lipid modification, confers unique biochemical and functional properties to proteins. Although it has long been known that viral proteins are palmitoylated, recent studies reveal that this modification plays a critical role for pathogens of all kinds and at multiple steps of their life cycle. The present review examines the involvement of S-palmitoylation in infection by viruses, bacteria and parasites and illustrates how pathogens have evolved to manipulate the host palmitoylation machinery.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://sonar.ch/global/documents/212227
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