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Electrochemical imaging of cells and tissues.
Journal article

Electrochemical imaging of cells and tissues.

  • Lin TE Laboratory of Physical and Analytical Electrochemistry (LEPA) , École Polytechnique Fédéderale de Lausanne , EPFL Valais Valais , Rue de l'Industrie 17 , CP 440 , 1951 Sion , Switzerland . Email: andreas.lesch@epfl.ch.
  • Rapino S Chemistry Department "Giacomo Ciamician" , University of Bologna , Via Selmi 2 , 40126 Bologna , Italy.
  • Girault HH Laboratory of Physical and Analytical Electrochemistry (LEPA) , École Polytechnique Fédéderale de Lausanne , EPFL Valais Valais , Rue de l'Industrie 17 , CP 440 , 1951 Sion , Switzerland . Email: andreas.lesch@epfl.ch.
  • Lesch A Laboratory of Physical and Analytical Electrochemistry (LEPA) , École Polytechnique Fédéderale de Lausanne , EPFL Valais Valais , Rue de l'Industrie 17 , CP 440 , 1951 Sion , Switzerland . Email: andreas.lesch@epfl.ch.
  • 2018-06-15
Published in:
  • Chemical science. - 2018
General Chemistry
English The technological and experimental progress in electrochemical imaging of biological specimens is discussed with a view on potential applications for skin cancer diagnostics, reproductive medicine and microbial testing. The electrochemical analysis of single cell activity inside cell cultures, 3D cellular aggregates and microtissues is based on the selective detection of electroactive species involved in biological functions. Electrochemical imaging strategies, based on nano/micrometric probes scanning over the sample and sensor array chips, respectively, can be made sensitive and selective without being affected by optical interference as many other microscopy techniques. The recent developments in microfabrication, electronics and cell culturing/tissue engineering have evolved in affordable and fast-sampling electrochemical imaging platforms. We believe that the topics discussed herein demonstrate the applicability of electrochemical imaging devices in many areas related to cellular functions.
Language
  • English
Open access status
gold
Identifiers
Persistent URL
https://sonar.ch/global/documents/212572
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