Killing Mechanisms of Cytotoxic T Lymphocytes.
- Groscurth P Division of Cell Biology, Institute of Anatomy, University of Zürich-Irchel, Winterhurerstrasse 190, CH-8057 Zurich, Switzerland.
- Filgueira L
- 2001-06-08
Published in:
- News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society. - 1998
English
Cytotoxic T lymphocytes mediate lysis of target cells by various mechanisms, including exocytosis of lytic proteins (perforin, granzymes) and receptor-ligand binding of Fas/APO molecules. Death of target cells is characterized by either necrosis or apoptosis, depending on the killing mechanism used and on the metabolism of the target cell itself.
- Language
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- English
- Open access status
- green
- Identifiers
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- DOI 10.1152/physiologyonline.1998.13.1.17
- PMID 11390753
- Persistent URL
- https://sonar.ch/global/documents/213294
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