An overview of recent developments in FLUKA PET tools.
- Augusto RS CERN - European Organization for Nuclear Research, CH-1211 Genève 23, Switzerland; Ludwig-Maximilians-Universität München, Am Coulombwall 1, 85748 Garching, Germany. Electronic address: r.s.augusto@cern.ch.
- Bauer J UniversitätsKlinikum Heidelberg, Heidelberger Ionenstrahl-Therapiezentrum HIT, Germany.
- Bouhali O Texas A&M University at Qatar, 23874 Doha, Qatar.
- Cuccagna C CERN - European Organization for Nuclear Research, CH-1211 Genève 23, Switzerland; TERA Foundation, Via Puccini 11, 28100 Novara, Italy; Université de Genève, 30 quai Ernest-Ansermet, CH-1211 Genève, Switzerland.
- Gianoli C Ludwig-Maximilians-Universität München, Am Coulombwall 1, 85748 Garching, Germany.
- Kozłowska WS CERN - European Organization for Nuclear Research, CH-1211 Genève 23, Switzerland; Medizinische Universität Wien, Spitalgasse 23, 1090 Vienna, Austria.
- Ortega PG Grupo de Física Nuclear, Universidad de Salamanca, E-37008 Salamanca, Spain.
- Tessonnier T Centre François Baclesse, 3 Avenue du Général Harris, 14000 Caen, France.
- Toufique Y Texas A&M University at Qatar, 23874 Doha, Qatar; Institut Superieur des Sciences de la Santé de Settat, Morocco.
- Vlachoudis V CERN - European Organization for Nuclear Research, CH-1211 Genève 23, Switzerland.
- Parodi K Ludwig-Maximilians-Universität München, Am Coulombwall 1, 85748 Garching, Germany.
- Ferrari A CERN - European Organization for Nuclear Research, CH-1211 Genève 23, Switzerland.
- 2018-07-19
Published in:
- Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB). - 2018
FLUKA
Monte Carlo
PET
Image Processing, Computer-Assisted
Monte Carlo Method
Positron-Emission Tomography
Signal-To-Noise Ratio
English
The new developments of the FLUKA Positron-Emission-Tomography (PET) tools are detailed. FLUKA is a fully integrated Monte Carlo (MC) particle transport code, used for an extended range of applications, including Medical Physics. Recently, it provided the medical community with dedicated simulation tools for clinical applications, including the PET simulation package. PET is a well-established imaging technique in nuclear medicine, and a promising method for clinical in vivo treatment verification in hadrontherapy. The application of clinically established PET scanners to new irradiation environments such as hadrontherapy requires further experimental and theoretical research to which MC simulations could be applied. The FLUKA PET tools, besides featuring PET scanner models in its library, allow the configuration of new PET prototypes via the FLUKA Graphical User Interface (GUI) Flair. Both the beam time structure and scan time can be specified by the user, reproducing PET acquisitions in time, in a particle therapy scenario. Furthermore, different scoring routines allow the analysis of single and coincident events, and identification of parent isotopes generating annihilation events. Two reconstruction codes are currently supported: the Filtered Back-Projection (FBP) and Maximum-Likelihood Expectation Maximization (MLEM), the latter embedded in the tools. Compatibility with other reconstruction frameworks is also possible. The FLUKA PET tools package has been successfully tested for different detectors and scenarios, including conventional functional PET applications and in beam PET, either using radioactive sources, or simulating hadron beam irradiations. The results obtained so far confirm the FLUKA PET tools suitability to perform PET simulations in R&D environment.
- Language
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- English
- Open access status
- hybrid
- Identifiers
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- DOI 10.1016/j.ejmp.2018.06.636
- PMID 30017561
- Persistent URL
- https://sonar.ch/global/documents/213794
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