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Intravitreal fluocinolone acetonide implant (ILUVIEN®) for diabetic macular oedema: a literature review.

  • Massa H 1 Department of Ophthalmology, Geneva University Hospitals, Geneva, Switzerland.
  • Nagar AM 2 Eye Treatment Centre, Whipps Cross University Hospital, Barts Health NHS Trust, London, UK.
  • Vergados A 2 Eye Treatment Centre, Whipps Cross University Hospital, Barts Health NHS Trust, London, UK.
  • Dadoukis P 2 Eye Treatment Centre, Whipps Cross University Hospital, Barts Health NHS Trust, London, UK.
  • Patra S 2 Eye Treatment Centre, Whipps Cross University Hospital, Barts Health NHS Trust, London, UK.
  • Panos GD 2 Eye Treatment Centre, Whipps Cross University Hospital, Barts Health NHS Trust, London, UK.
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  • 2018-12-18
Published in:
  • The Journal of international medical research. - 2019
Diabetic macular oedema
ILUVIEN
anti-VEGF agents
diabetes
diabetic retinopathy
fluocinolone acetonide
intravitreal injections
steroid implant
Angiogenesis Inhibitors
Anti-Inflammatory Agents
Diabetic Retinopathy
Drug Implants
Fluocinolone Acetonide
Humans
Intravitreal Injections
Light Coagulation
Low-Level Light Therapy
Macular Edema
Patient Safety
Treatment Outcome
Vascular Endothelial Growth Factor A
English Diabetic macular oedema (DMO) is a common complication of diabetic retinopathy and may lead to severe visual loss. In this review, we describe the pathophysiology of DMO and review current therapeutic options such as macular laser photocoagulation, anti-vascular endothelial growth factor agents, and steroid implants with a focus on the new fluocinolone acetonide implant, ILUVIEN®. The results of the Fluocinolone Acetonide in Diabetic Macular Edema (FAME) studies are also presented together with the results of real-world studies to support the clinical use of ILUVIEN® in achieving efficient resolution of DMO and improving vision and macular anatomy in this challenging group of patients.
Language
  • English
Open access status
gold
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https://sonar.ch/global/documents/216109
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