Rapid spread of double East- and West-African kdr mutations in wild Anopheles coluzzi from Côte d'Ivoire.
Journal article

Rapid spread of double East- and West-African kdr mutations in wild Anopheles coluzzi from Côte d'Ivoire.

  • Mouhamadou CS Centre Suisse de Recherches Scientifiques, Abidjan, Cote d'Ivoire.
  • N'Dri PB Centre Suisse de Recherches Scientifiques, Abidjan, Cote d'Ivoire.
  • Fodjo BK Centre Suisse de Recherches Scientifiques, Abidjan, Cote d'Ivoire.
  • Sadia CG Centre Suisse de Recherches Scientifiques, Abidjan, Cote d'Ivoire.
  • Affoue FK Centre Suisse de Recherches Scientifiques, Abidjan, Cote d'Ivoire.
  • Koudou BG Centre Suisse de Recherches Scientifiques, Abidjan, Cote d'Ivoire.
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  • 2019-04-26
Published in:
  • Wellcome open research. - 2019
English Malaria morbidity and mortality rates in Sub-Saharan Africa are increasing. The scale-up of long-lasting insecticidal nets and indoor residual spraying have been the major contributors to the decrease of malaria burden. These tools are now threatened by insecticide resistance in malaria vectors, which is spreading dramatically. After two different real-time polymerase chain reaction molecular characterizations carried out on 70 mosquitoes sampled in the locality of Elibou in southern Côte d'Ivoire, results revealed that 9 mosquitoes from Anopheles coluzzi harbored the double East- and West-African knockdown resistance mutations. In the previous year, only 1 mosquito out of 150 sampled from 10 regions of the country had the same genotype. These results show the rapid spread of insecticide resistance in malaria vectors and highlight the urgent need to diversify the methods of vector control in order to avoid the failure of insecticide-based vector control tools which may favor malaria fatalities.
Language
  • English
Open access status
gold
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Persistent URL
https://sonar.ch/global/documents/216788
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