Toscana virus meningitis case in Switzerland: an example of the ezVIR bioinformatics pipeline utility for the identification of emerging viruses.
-
Cordey S
Swiss National Reference Centre for Emerging Viral Infections, University of Geneva Hospitals, Geneva, Switzerland; Laboratory of Virology, Infectious Diseases Service, University Hospitals of Geneva, Geneva, Switzerland; University of Geneva Medical School, Geneva, Switzerland. Electronic address: samuel.cordey@hcuge.ch.
-
Bel M
Swiss National Reference Centre for Emerging Viral Infections, University of Geneva Hospitals, Geneva, Switzerland; Laboratory of Virology, Infectious Diseases Service, University Hospitals of Geneva, Geneva, Switzerland; University of Geneva Medical School, Geneva, Switzerland.
-
Petty TJ
Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland; Swiss Institute of Bioinformatics, Geneva, Switzerland.
-
Docquier M
University of Geneva Medical School and Genomics Platform, Geneva, Switzerland.
-
Sacco L
Swiss National Reference Centre for Emerging Viral Infections, University of Geneva Hospitals, Geneva, Switzerland; Laboratory of Virology, Infectious Diseases Service, University Hospitals of Geneva, Geneva, Switzerland; University of Geneva Medical School, Geneva, Switzerland.
-
Turin L
Laboratory of Virology, Infectious Diseases Service, University Hospitals of Geneva, Geneva, Switzerland; University of Geneva Medical School, Geneva, Switzerland.
-
Cherpillod P
Swiss National Reference Centre for Emerging Viral Infections, University of Geneva Hospitals, Geneva, Switzerland; Laboratory of Virology, Infectious Diseases Service, University Hospitals of Geneva, Geneva, Switzerland; University of Geneva Medical School, Geneva, Switzerland.
-
Emonet S
Laboratory of Bacteriology, University Hospitals of Geneva & Medical School, Geneva, Switzerland.
-
Louis-Simonet M
Internal Medicine Department, University Hospitals of Geneva & Medical School, Geneva, Switzerland.
-
Zdobnov EM
Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland; Swiss Institute of Bioinformatics, Geneva, Switzerland; Imperial College London, South Kensington Campus, London, UK.
-
Ambrosioni J
Laboratory of Virology, Infectious Diseases Service, University Hospitals of Geneva, Geneva, Switzerland; University of Geneva Medical School, Geneva, Switzerland.
-
Kaiser L
Swiss National Reference Centre for Emerging Viral Infections, University of Geneva Hospitals, Geneva, Switzerland; Laboratory of Virology, Infectious Diseases Service, University Hospitals of Geneva, Geneva, Switzerland; University of Geneva Medical School, Geneva, Switzerland.
Show more…
Published in:
- Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. - 2015
English
Toscana virus (TOSV) represents a frequent cause of viral meningitis in the Mediterranean Basin that remains neglected in neighbouring countries. We report a documented TOSV meningitis case in a traveller returning from Tuscany to Switzerland. While routine serological and PCR assays could not discriminate between TOSV and Sandfly fever Naples virus infection, a high-throughput sequencing performed directly on the cerebrospinal fluid specimen and analysed with the ezVIR pipeline provided an unequivocal viral diagnostic. TOSV could be unequivocally considered as the aetiological agent, proving the potential of ezVIR to improve standard diagnostics in cases of infection with uncommon or emerging viruses.
-
Language
-
-
Open access status
-
hybrid
-
Identifiers
-
-
Persistent URL
-
https://sonar.ch/global/documents/221443
Statistics
Document views: 14
File downloads: