Back
Cell-mediated delivery of synthetic nano- and microparticles.
Journal article

Cell-mediated delivery of synthetic nano- and microparticles.

  • Ayer M École Polytechnique Fédérale de Lausanne (EPFL), Institut des Matériaux and Institut des Sciences et Ingénierie Chimiques, Laboratoire des Polymères, Bâtiment MXD, Station 12, CH-1015 Lausanne, Switzerland. Electronic address: maxime.ayer@epfl.ch.
  • Klok HA École Polytechnique Fédérale de Lausanne (EPFL), Institut des Matériaux and Institut des Sciences et Ingénierie Chimiques, Laboratoire des Polymères, Bâtiment MXD, Station 12, CH-1015 Lausanne, Switzerland. Electronic address: harm-anton.klok@epfl.ch.
  • 2017-02-13
Published in:
  • Journal of controlled release : official journal of the Controlled Release Society. - 2017
Cell surface-conjugation
Cell-mediated drug delivery
Cellular backpacks
Cellular hitchhiking
Nano- and microparticles
Animals
Drug Delivery Systems
Erythrocytes
Humans
Leukocytes
Nanoparticles
Stem Cells
English Cell mediated delivery of synthetic nano- and microparticle based drug carriers is a very promising strategy to enhance control over the distribution of drugs and improve targeting. This article will present an overview of work, which has been done to explore cell surface modification strategies for the cellular hitchhiking of synthetic nano- and microparticles. The first part of this article will present and discuss the different types of cells that have been explored for cell mediated drug delivery. The second part of this review will discuss the various chemical strategies that have been elaborated for the conjugation or immobilization of nano- and microparticles on the surface of these cells.
Language
  • English
Open access status
green
Identifiers
Persistent URL
https://sonar.ch/global/documents/22184
Statistics
Document views: 42 File downloads: