100 years of peroxynitrite chemistry and 11 years of peroxynitrite biochemistry.

Koppenol WH

doi:10.1179/135100001101536517

Back

Journal article

100 years of peroxynitrite chemistry and 11 years of peroxynitrite biochemistry.

Koppenol WH Laboratorium für Anorganische Chemie, Eidgenössische Technische Hochschule, Zürich, Switzerland. koppenol@inorg.chem.ethz.ch

2002-02-28

Published in:

Redox report : communications in free radical research. - 2001

English The paper on the unusual properties of a mixture of hydrogen peroxide and nitrous acid by Baeyer and Villiger from 1901 can be regarded as the first report on peroxynitrite. In 1990, Beckman and co-workers suggested that peroxynitrite, formed from the reaction of superoxide with nitrogen monoxide, could be a transient oxidizing species in vivo, a report that revolutionized investigations in the field of oxidative stress.

Language