Journal article
Titanium and hydroxyapatite coating of polyetheretherketone and carbon fiber-reinforced polyetheretherketone: A pilot study in sheep.
- Stübinger S Hightech Research Center of Cranio-Maxillofacial Surgery, University of Basel, CH-4031, Basel, Switzerland.
- Drechsler A Hightech Research Center of Cranio-Maxillofacial Surgery, University of Basel, CH-4031, Basel, Switzerland.
- Bürki A Institute for Surgical Biotechnology and Biomechanics, University of Bern, CH-3014, Bern, Switzerland.
- Klein K Hightech Research Center of Cranio-Maxillofacial Surgery, University of Basel, CH-4031, Basel, Switzerland.
- Kronen P Center for Applied Biotechnology and Molecular Medicine (CABMM), Vetsuisse Faculty, University of Zurich, CH-8057, Zurich, Switzerland.
- von Rechenberg B Hightech Research Center of Cranio-Maxillofacial Surgery, University of Basel, CH-4031, Basel, Switzerland.
- 2015-06-23
Published in:
- Journal of biomedical materials research. Part B, Applied biomaterials. - 2016
CFR-PEEK
osseointegration
polyetheretherketone
pull-out test
sheep
Animals
Carbon
Coated Materials, Biocompatible
Durapatite
Implants, Experimental
Ketones
Osseointegration
Pilot Projects
Polyethylene Glycols
Sheep
Titanium
English
PURPOSE
The purpose of this study was to evaluate the bone formation capability of polyetheretherketone (PEEK) and carbon fiber-reinforced PEEK (CFR-PEEK) implants coated with different titanium and hydroxyapatite plasma-sprayed layers after 2 and 12 weeks.
METHODS
In six sheep 108 implants were placed in the pelvis. Altogether six different surface modifications were tested. After 2 and 12 weeks, n = 3 implants per group were examined histologically and n = 6 implants per group were tested by a pull-out test.
RESULTS
Biomechanically (p = 0.001) as well as histologically (p > 0.05) surface coating of PEEK/CFR-PEEK led to an increase of osseointegration from 2 to 12 weeks. After 12 weeks, coated implants demonstrated significant (p < 0.001) higher pull-out values in comparison to uncoated implants. Overall, the double coating (titanium bond layer and hydroxyapatite top layer) showed the most favorable results after 2 and 12 weeks.
CONCLUSIONS
Plasma-sprayed titanium and hydroxyapatite coatings on PEEK or CFR-PEEK demonstrated a significant improvement of osseointegration. © 2015 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 104B: 1182-1191, 2016.
The purpose of this study was to evaluate the bone formation capability of polyetheretherketone (PEEK) and carbon fiber-reinforced PEEK (CFR-PEEK) implants coated with different titanium and hydroxyapatite plasma-sprayed layers after 2 and 12 weeks.
METHODS
In six sheep 108 implants were placed in the pelvis. Altogether six different surface modifications were tested. After 2 and 12 weeks, n = 3 implants per group were examined histologically and n = 6 implants per group were tested by a pull-out test.
RESULTS
Biomechanically (p = 0.001) as well as histologically (p > 0.05) surface coating of PEEK/CFR-PEEK led to an increase of osseointegration from 2 to 12 weeks. After 12 weeks, coated implants demonstrated significant (p < 0.001) higher pull-out values in comparison to uncoated implants. Overall, the double coating (titanium bond layer and hydroxyapatite top layer) showed the most favorable results after 2 and 12 weeks.
CONCLUSIONS
Plasma-sprayed titanium and hydroxyapatite coatings on PEEK or CFR-PEEK demonstrated a significant improvement of osseointegration. © 2015 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 104B: 1182-1191, 2016.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1002/jbm.b.33471
- PMID 26097161
- Persistent URL
- https://sonar.ch/global/documents/22510
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