Journal article
Natural iron isotope variations in human blood.
- Walczyk T Laboratory of Human Nutrition, Institute of Food Sciences, Swiss Federal Institute of Technology (ETH) Zurich, Seestrasse 72, CH-8803 Rüschlikon, Switzerland. thomas.walczyk@ilw.agrl.ethz.ch
- von Blanckenburg F
- 2002-03-16
Published in:
- Science (New York, N.Y.). - 2002
Adult
Animals
Child
Female
Food Analysis
Humans
Infant
Intestinal Absorption
Iron
Iron Isotopes
Iron, Dietary
Liver
Male
Meat
Muscles
Reference Values
Sex Characteristics
English
Isotopic analysis of human blood and liver and muscle tissue indicates that each individual bears a long-term iron (Fe) isotope signature in the blood. Blood and tissue differ slightly in isotopic composition and are depleted by up to 2.6 per mil in 56Fe relative to 54Fe when compared to dietary Fe. The 56Fe/54Fe isotope ratio in the blood of males is, on average, lower by 0.3 per mil than that of females. These results suggest that Fe isotope effects in the blood reflect differences in intestinal Fe absorption between individuals and genotypes.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1126/science.1069389
- PMID 11896276
- Persistent URL
- https://sonar.ch/global/documents/228193
Statistics
Document views: 52
File downloads: