Advances in venomics.
Journal article

Advances in venomics.

  • Oldrati V Atheris SA, Chemin d'Alcire 1, CH-1228 Plan-les-Ouates, Geneva, Switzerland. contact@atheris.com and School of Pharmaceutical Sciences, EPGL, University of Geneva, University of Lausanne, CMU, 1, Rue Michel Servet, CH-1211 Geneva 4, Switzerland.
  • Arrell M Atheris SA, Chemin d'Alcire 1, CH-1228 Plan-les-Ouates, Geneva, Switzerland. contact@atheris.com.
  • Violette A Alphabiotoxine Laboratory Sprl, Montroeul-au-Bois B-7911, Belgium.
  • Perret F Atheris SA, Chemin d'Alcire 1, CH-1228 Plan-les-Ouates, Geneva, Switzerland. contact@atheris.com.
  • Sprüngli X Atheris SA, Chemin d'Alcire 1, CH-1228 Plan-les-Ouates, Geneva, Switzerland. contact@atheris.com.
  • Wolfender JL School of Pharmaceutical Sciences, EPGL, University of Geneva, University of Lausanne, CMU, 1, Rue Michel Servet, CH-1211 Geneva 4, Switzerland.
  • Stöcklin R Atheris SA, Chemin d'Alcire 1, CH-1228 Plan-les-Ouates, Geneva, Switzerland. contact@atheris.com.
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  • 2016-10-28
Published in:
  • Molecular bioSystems. - 2016
English The term "venomics" was coined to describe the global study of venom and venom glands, targeting comprehensive characterization of the whole toxin profile of a venomous animal by means of proteomics, transcriptomics, genomics and bioinformatics studies. This integrative approach is supported by the rapid evolution of protein, RNA and DNA sequencing techniques, as well as databases, knowledge-bases and biocomputing algorithms. The aim of this review is to illustrate advances in the field of venomics during the last decade, addressing each step of the procedure, from sample collection to data treatment. A special focus is made on new perspectives for a better understanding of the venomous function and for fostering the discovery of new venom-derived drug candidates.
Language
  • English
Open access status
closed
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Persistent URL
https://sonar.ch/global/documents/229649
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