Deletion in the gene BruAb2_0168 of Brucella abortus strains: diagnostic challenges.
- Dean AS Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland.
- Schelling E
- Bonfoh B
- Kulo AE
- Boukaya GA
- Pilo P
- 2014-01-24
Published in:
- Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. - 2014
Brucella
Togo
cattle
diagnostics
genotyping
Animals
Brucella abortus
Cattle
Cattle Diseases
DNA, Bacterial
Diagnostic Errors
Genes, Bacterial
Lymphangioma, Cystic
Molecular Diagnostic Techniques
Molecular Sequence Data
Sequence Analysis, DNA
Sequence Deletion
Togo
English
Three Brucella abortus strains were isolated from joint hygromas from cows in northern Togo. Two deletions in the 5' side of the gene BruAb2_0168 were identified. As this gene is used for species identification, these deletions have consequences for diagnostic procedures. Multiple locus variable number of tandem repeat (VNTR) analysis was therefore performed for species identification. The strains showed unique VNTR profiles, providing some of the first genotypic data from West Africa. More molecular and epidemiological data are needed from the region, in order to better understand transmission patterns and develop suitable diagnostic assays.
- Language
-
- English
- Open access status
- hybrid
- Identifiers
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- DOI 10.1111/1469-0691.12554
- PMID 24450581
- Persistent URL
- https://sonar.ch/global/documents/232225
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