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Modeling neuronal vulnerability in ALS.
Roselli F
Friedrich Miescher Institute for Biomedical Research, 4058 Basel, Switzerland.
Caroni P
Friedrich Miescher Institute for Biomedical Research, 4058 Basel, Switzerland. Electronic address: pico.caroni@fmi.ch.
2014-08-22
Published in:
Neuron. - 2014
Action Potentials
Energy Metabolism
Models, Neurological
Motor Neurons
Nerve Degeneration
English
Using computational models of motor neuron ion fluxes, firing properties, and energy requirements, Le Masson et al. (2014) reveal how local imbalances in energy homeostasis may self-amplify and contribute to neurodegeneration in ALS.
Language
English
Open access status
bronze
Identifiers
DOI
10.1016/j.neuron.2014.08.010
PMID
25144872
Persistent URL
https://sonar.ch/global/documents/232352
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