solarius: an R interface to SOLAR for variance component analysis in pedigrees.
- Ziyatdinov A Unitat De Genòmica De Malalties Complexes, Institut D'investigació Biomèdica Sant Pau (IIB-Sant Pau), Barcelona, Spain.
- Brunel H Unitat De Genòmica De Malalties Complexes, Institut D'investigació Biomèdica Sant Pau (IIB-Sant Pau), Barcelona, Spain.
- Martinez-Perez A Unitat De Genòmica De Malalties Complexes, Institut D'investigació Biomèdica Sant Pau (IIB-Sant Pau), Barcelona, Spain.
- Buil A Department of Genetics Medicine and Development, University of Geneva Medical School, Geneva, Switzerland.
- Perera A B2SLab, Department ESAII, Universitat Politècnica De Catalunya, Barcelona, Spain CIBER in Bioengineering Biomaterials and Nanomedicine, Barcelona, Spain.
- Soria JM Unitat De Genòmica De Malalties Complexes, Institut D'investigació Biomèdica Sant Pau (IIB-Sant Pau), Barcelona, Spain.
- 2016-05-07
Published in:
- Bioinformatics (Oxford, England). - 2016
Analysis of Variance
Genetic Linkage
Genome-Wide Association Study
Humans
Linkage Disequilibrium
Models, Statistical
Multivariate Analysis
Pedigree
Quantitative Trait Loci
Software
English
UNLABELLED
: The open source environment R is one of the most widely used software for statistical computing. It provides a variety of applications including statistical genetics. Most of the powerful tools for quantitative genetic analyses are stand-alone free programs developed by researchers in academia. SOLAR is one of the standard software programs to perform linkage and association mappings of the quantitative trait loci (QTLs) in pedigrees of arbitrary size and complexity. solarius allows the user to exploit the variance component methods implemented in SOLAR. It automates such routine operations as formatting pedigree and phenotype data. It parses also the model output and contains summary and plotting functions for exploration of the results. In addition, solarius enables parallel computing of the linkage and association analyses that makes the calculation of genome-wide scans more efficient.
AVAILABILITY AND IMPLEMENTATION
solarius is available on CRAN and on GitHub https://github.com/ugcd/solarius
CONTACT
: aziyatdinov@santpau.cat.
: The open source environment R is one of the most widely used software for statistical computing. It provides a variety of applications including statistical genetics. Most of the powerful tools for quantitative genetic analyses are stand-alone free programs developed by researchers in academia. SOLAR is one of the standard software programs to perform linkage and association mappings of the quantitative trait loci (QTLs) in pedigrees of arbitrary size and complexity. solarius allows the user to exploit the variance component methods implemented in SOLAR. It automates such routine operations as formatting pedigree and phenotype data. It parses also the model output and contains summary and plotting functions for exploration of the results. In addition, solarius enables parallel computing of the linkage and association analyses that makes the calculation of genome-wide scans more efficient.
AVAILABILITY AND IMPLEMENTATION
solarius is available on CRAN and on GitHub https://github.com/ugcd/solarius
CONTACT
: aziyatdinov@santpau.cat.
- Language
-
- English
- Open access status
- bronze
- Identifiers
-
- DOI 10.1093/bioinformatics/btw080
- PMID 27153684
- Persistent URL
- https://sonar.ch/global/documents/232448
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