Journal article

Breast Fibroadenoma With Increased Activity on 68Ga DOTATATE PET/CT.

  • Papadakis GZ From the *Department of Radiology and Imaging Sciences, Warren Grant Magnuson Clinical Center, †PET Department, Clinical Center, and ‡Endocrine Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD; §Endocrine and Thoracic Surgery, University Hospitals of Geneva, Geneva, Switzerland; ∥Department of Radiology, Medical School, University of Crete, Greece; and ¶Center for Research in Computer Vision, Electrical and Computer Science Department, University of Central Florida, Orlando, FL.
  • Millo C
  • Sadowski SM
  • Karantanas AH
  • Bagci U
  • Patronas NJ
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  • 2016-11-24
Published in:
  • Clinical nuclear medicine. - 2017
English Fibroadenoma is the most common benign breast tumor in women of reproductive age, carrying little to no risk of breast cancer development. We report on a case of a woman with history of neuroendocrine tumor who on follow-up imaging tests underwent whole-body PET/CT study using Ga DOTATATE. The scan showed increased focal activity in the right breast, which was biopsied revealing a fibroadenoma. The presented data suggests cell surface overexpression of somatostatin receptors by this benign breast tumor. Moreover, this finding emphasizes the need for cautious interpretation of Ga DOTATATE-avid breast lesions that could mimic malignancy in neuroendocrine tumor patients.
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  • English
Open access status
green
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https://sonar.ch/global/documents/232637
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