Conflicting verdicts on peanut oral immunotherapy from the Institute for Clinical and Economic Review and US Food and Drug Administration Advisory Committee: Where do we go from here?

• Eiwegger T Division of Immunology and Allergy, Food Allergy and Anaphylaxis Program, Department of Pediatrics, Hospital for Sick Children, Toronto, Canada; Research Institute, Translational Medicine, Hospital for Sick Children, Toronto, Canada; Department of Immunology, University of Toronto, Toronto, Canada.
• Anagnostou K Department of Pediatrics, Section of Immunology, Allergy and Retrovirology, Texas Children's Hospital, Houston, Tex; Baylor College of Medicine, Houston, Tex.
• Arasi S Department of Pediatric Medicine, Pediatric Allergology Unit, Bambino Gesù Children's research Hospital (IRCCS), Rome, Italy.
• Bégin P Division of Immunology and Allergy, Department of Pediatrics, CHU Ste-Justine, Montreal, Canada; Division of Immunology and Allergy, Department of Medicine, Centre Hospitalier de l'Université de Montréal, Montreal, Canada.
• Ben-Shoshan M Division of Pediatric Allergy and Clinical Immunology, Department of Pediatrics, McGill University Health Center, Montreal, Canada.
• Beyer K Department of Pediatric Pneumology, Immunology and Intensive Care, Charité Universitätsmedizin Berlin, Berlin, Germany.
• Blumchen K Department of Children and Adolescent Medicine, Division of Pneumology, Allergology and Cystic fibrosis, University Hospital Frankfurt, Frankfurt am Main, Germany.
• Brough H Department of Women and Children's Health (Pediatric Allergy), School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom; Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London, United Kingdom; Children's Allergy Service, Evelina London, Guy's and St Thomas' Hospital, London, United Kingdom.
• Caubet JC Division of Pediatric Allergy, Department of Pediatrics, University Hospitals of Geneva, Geneva, Switzerland.
• Chan ES Division of Allergy and Immunology, Department of Pediatrics, University of British Columbia, BC Children's Hospital, Vancouver, British Columbia, Canada.
• Chen M Sean N. Parker Center for Allergy and Asthma Research at Stanford University, Stanford, Calif; Division of Pulmonary and Critical Care Medicine, Stanford, Calif.
• Chinthrajah S Sean N. Parker Center for Allergy and Asthma Research at Stanford University, Stanford, Calif; Division of Pulmonary and Critical Care Medicine, Stanford, Calif.
• Davis CM Department of Pediatrics, Section of Immunology, Allergy and Retrovirology, Texas Children's Hospital, Houston, Tex; Baylor College of Medicine, Houston, Tex.
• Des Roches A Division of Immunology and Allergy, Department of Pediatrics, CHU Ste-Justine, Montreal, Canada.
• Du Toit G Department of Women and Children's Health (Pediatric Allergy), School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom; Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London, United Kingdom; Children's Allergy Service, Evelina London, Guy's and St Thomas' Hospital, London, United Kingdom.
• Elizur A Institute of Allergy, Immunology and Pediatric Pulmonology, Yitzhak Shamir Medical Center and Department of Pediatrics, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
• Galli SJ Sean N. Parker Center for Allergy and Asthma Research at Stanford University, Stanford, Calif; Department of Pathology and Department of Microbiology and Immunology, Stanford, Calif.
• Håland G Department of Paediatric Allergy and Pulmonology, Oslo University Hospital, Oslo, Norway.
• Hoffmann-Sommergruber K Department of Pathophysiology and Allergy Research, Medical University of Vienna, Vienna, Austria.
• Kim H Division of Clinical Immunology and Allergy, Department of Medicine, Western University, London, Canada; Division of Clinical Immunology and Allergy, Department of Medicine, McMaster University, Hamilton, Canada.
• Leung DYM Department of Pediatrics, National Jewish Health, Denver, and the Department of Pediatrics, University of Colorado at Denver Health Sciences Center, Aurora, Colo.
• Long A Sean N. Parker Center for Allergy and Asthma Research at Stanford University, Stanford, Calif; Division of Pulmonary and Critical Care Medicine, Stanford, Calif.
• Muraro A Food Allergy Centre-Veneto Region, Department of Woman and Child Health Padua University Hospital, Padua, Italy.
• Nurmatov UB Division of Population Medicine, School of Medicine, National Centre for Population Health and Wellbeing Research, Swansea, United Kingdom.
• Pajno GB Department of Pediatrics, Allergy Unit, University of Messina, Messina, Italy.
• Sampath V Sean N. Parker Center for Allergy and Asthma Research at Stanford University, Stanford, Calif; Division of Pulmonary and Critical Care Medicine, Stanford, Calif.
• Saxena J Sean N. Parker Center for Allergy and Asthma Research at Stanford University, Stanford, Calif; Division of Pulmonary and Critical Care Medicine, Stanford, Calif.
• Sindher S Sean N. Parker Center for Allergy and Asthma Research at Stanford University, Stanford, Calif; Division of Pulmonary and Critical Care Medicine, Stanford, Calif.
• Upton J Division of Immunology and Allergy, Food Allergy and Anaphylaxis Program, Department of Pediatrics, Hospital for Sick Children, Toronto, Canada.
• Worm M Division of Allergy and Immunology, Department of Dermatology, Allergy and Venerology, Charité Universitätsmedizin Berlin, Berlin, Germany.
• Nadeau KC Sean N. Parker Center for Allergy and Asthma Research at Stanford University, Stanford, Calif; Division of Pulmonary and Critical Care Medicine, Stanford, Calif; Division of Allergy, Immunology and Rheumatology, Stanford University, Stanford, Calif. Electronic address: knadeau@stanford.edu.

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Food allergy

Institute for Clinical and Economic Review

US Food and Drug Administration Allergenic Products Advisory Committee

efficacy

management

peanut allergy

quality of life

safety

treatment