The Montreux definition of neonatal ARDS: biological and clinical background behind the description of a new entity.
Journal article

The Montreux definition of neonatal ARDS: biological and clinical background behind the description of a new entity.

  • De Luca D Division of Paediatrics and Neonatal Critical Care, Hôpital Antoine-Béclère, GHU Paris Sud-APHP and South Paris University, Paris, France; Institute of Anaesthesiology and Critical Care, Agostino Gemelli University Polyclinic, Catholic University of the Sacred Heart, Rome, Italy. Electronic address: daniele.deluca@aphp.fr.
  • van Kaam AH Department of Neonatology, Emma Children's Hospital Academic Medical Center, Amsterdam, Netherlands.
  • Tingay DG Neonatal Research, Murdoch Childrens Research Institute, Department of Neonatology, Royal Children's Hospital and Department of Paediatrics, University of Melbourne, Melbourne, VIC, Australia.
  • Courtney SE Department of Paediatrics, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
  • Danhaive O Division of Pediatrics, Zuckerberg San Francisco General Hospital, and Department of Pediatrics University of California, San Francisco, CA, USA.
  • Carnielli VP Division of Neonatology, G Salesi Women's and Children Hospital, Polytechnical University of Marche, Ancona, Italy.
  • Zimmermann LJ Department of Paediatrics-Neonatology, Research School for Oncology and Developmental Biology, Maastricht UMC, Maastricht, Netherlands.
  • Kneyber MCJ Department of Pediatrics, Division of Pediatric Intensive Care, Beatrix Children's Hospital, University Medical Center Groningen, Groningen, Netherlands; Peri-operative Medicine and Emergency Medicine, University of Groningen, Groningen, Netherlands.
  • Tissieres P Division of Paediatric Critical Care and Neonatal Medicine, Hôpital Kremlin-Bicetre, GHU Paris Sud-APHP and South Paris University, Paris, France.
  • Brierley J Paediatric Intensive Care Unit, Great Ormond Street Hospital, London, UK.
  • Conti G Institute of Anaesthesiology and Critical Care, Agostino Gemelli University Polyclinic, Catholic University of the Sacred Heart, Rome, Italy.
  • Pillow JJ School of Human Sciences and Centre for Neonatal Research and Education, School of Medicine, The University of Western Australia, Perth, WA, Australia.
  • Rimensberger PC Division of Neonatology and Paediatric Critical Care, Department of Pediatrics, University Hospital of Geneva, Geneva, Switzerland.
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  • 2017-07-09
Published in:
  • The Lancet. Respiratory medicine. - 2017
English Acute respiratory distress syndrome (ARDS) is undefined in neonates, despite the long-standing existing formal recognition of ARDS syndrome in later life. We describe the Neonatal ARDS Project: an international, collaborative, multicentre, and multidisciplinary project which aimed to produce an ARDS consensus definition for neonates that is applicable from the perinatal period. The definition was created through discussions between five expert members of the European Society for Paediatric and Neonatal Intensive Care; four experts of the European Society for Paediatric Research; two independent experts from the USA and two from Australia. This Position Paper provides the first consensus definition for neonatal ARDS (called the Montreux definition). We also provide expert consensus that mechanisms causing ARDS in adults and older children-namely complex surfactant dysfunction, lung tissue inflammation, loss of lung volume, increased shunt, and diffuse alveolar damage-are also present in several critical neonatal respiratory disorders.
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  • English
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closed
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https://sonar.ch/global/documents/232807
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