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Prothrombotic hemostasis disturbances in patients with severe COVID-19: Individual daily data.
Journal article

Prothrombotic hemostasis disturbances in patients with severe COVID-19: Individual daily data.

  • Hardy M Université catholique de Louvain, CHU UCL Namur, Hematology Laboratory, Namur Thrombosis and Hemostasis Center (NTHC), Namur Research Institute for Life Sciences (NARILIS), Yvoir, Belgium.
  • Michaux I Université catholique de Louvain, CHU UCL Namur, Department of Intensive Care, Yvoir, Belgium.
  • Lessire S Université catholique de Louvain, CHU UCL Namur, Anesthesiology Department, Namur Thrombosis and hemostasis Center (NTHC), Namur Research Institute for Life Sciences (NARILIS), Yvoir, Belgium.
  • Douxfils J Department of Pharmacy, Namur Thrombosis and Hemostasis Center (NTHC), Namur Research Institute for Life Sciences (NARILIS), University of Namur, Namur, Belgium.
  • Dogné JM Department of Pharmacy, Namur Thrombosis and Hemostasis Center (NTHC), Namur Research Institute for Life Sciences (NARILIS), University of Namur, Namur, Belgium.
  • Bareille M Université catholique de Louvain, CHU UCL Namur, Hematology Laboratory, Namur Thrombosis and Hemostasis Center (NTHC), Namur Research Institute for Life Sciences (NARILIS), Yvoir, Belgium.
  • Horlait G Université catholique de Louvain, CHU UCL Namur, Department of Intensive Care, Yvoir, Belgium.
  • Bulpa P Université catholique de Louvain, CHU UCL Namur, Department of Intensive Care, Yvoir, Belgium.
  • Chapelle C Unité de Recherche Clinique, Innovation, Pharmacologie, CHU Saint-Etienne, Hôpital Nord, F-42055 Saint-Etienne, France.
  • Laporte S Unité de Recherche Clinique, Innovation, Pharmacologie, CHU Saint-Etienne, Hôpital Nord, F-42055 Saint-Etienne, France.
  • Testa S Haemostasis and Thrombosis Center, Cremona Hospital, Cremona, Italy.
  • Jacqmin H Université catholique de Louvain, CHU UCL Namur, Hematology Laboratory, Namur Thrombosis and Hemostasis Center (NTHC), Namur Research Institute for Life Sciences (NARILIS), Yvoir, Belgium.
  • Lecompte T Département de Médecine, Hôpitaux Universitaires de Genève, service d'angiologie et d'hémostase et Faculté de Médecine, Geneva Platelet Group (GpG), Université de Genève, Geneva, Switzerland.
  • Dive A Université catholique de Louvain, CHU UCL Namur, Department of Intensive Care, Yvoir, Belgium.
  • Mullier F Université catholique de Louvain, CHU UCL Namur, Hematology Laboratory, Namur Thrombosis and Hemostasis Center (NTHC), Namur Research Institute for Life Sciences (NARILIS), Yvoir, Belgium.
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  • 2020-11-17
Published in:
  • Data in brief. - 2020
COVID-19
D-dimers
Fibrinolysis
Hemostasis plasma proteins
Intensive care unit
Thrombin generation
Thrombosis
English This data article accompanies the manuscript entitled: "Prothrombotic Disturbances of hemostasis of Patients with Severe COVID-19: a Prospective Longitudinal Observational Cohort Study" submitted to Thrombosis Research by the same authors. We report temporal changes of plasma levels of an extended set of laboratory parameters during the ICU stay of the 21 COVID-19 patients included in the monocentre cohort: CRP, platelet count, prothrombin time; Clauss fibrinogen and clotting factors II, V and VIII levels, D-dimers, antithrombin activity, protein C, free protein S, total and free tissue factor pathway inhibitor, PAI-1 levels, von Willebrand factor antigen and activity, ADAMTS-13 (plasma levels); and of two integrative tests of coagulation (thrombin generation with ST Genesia) and fibrinolysis (global fibrinolytic capacity - GFC). Regarding hemostasis, we used double-centrifuged frozen citrated plasma prospectively collected after daily performance of usual coagulation tests. Demographic and clinical characteristics of patients and thrombotic and hemorrhagic complications were also collected from patient's electronic medical reports.
Language
  • English
Open access status
gold
Identifiers
Persistent URL
https://sonar.ch/global/documents/232992
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